Electrical impedance myography in the assessment of disuse atrophy.

Electrical impedance myography in the assessment of disuse atrophy.
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DOI:
10.1016/j.apmr.2009.04.007
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发表时间:
2009-10
影响因子:
4.3
通讯作者:
Rutkove, Seward B.
Rutkove, Seward B.
中科院分区:
医学1区
文献类型:
--
作者:
Tarulli, Andrew W.;Duggal, Naven;Esper, Gregory J.;Garmirian, Lindsay P.;Fogerson, Patricia M.;Lin, Connie H.;Rutkove, Seward B.

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使用电阻抗肌图(EIM)来量化废用性萎缩,这是一种我们已经成功地用于研究神经源性和肌病理性萎缩的非侵入性技术。我们对10例废用性萎缩继发于石膏固定的受试者和他们的健侧正常小腿进行了胫前肌EIM检查。受试者在摘除石膏后不久进行研究,并在摘除石膏并恢复正常活动能力后几周至几个月再次进行研究。三级护理医疗中心的神经科和骨科门诊。10名患有单侧小腿骨折的健康受试者。在50千赫时测量的电阻、电抗和相位。我们发现,在10例患者中,有9例的主要EIM结果参数--50 kHz的相位在固定的小腿中较低。此外,当恢复正常活动度时,所有10例患者的石膏腿相均较初始测量增加,而对侧小腿则不一致地增加。EIM可能是评估废用萎缩的有力工具。
To quantify disuse atrophy using electrical impedance myography (EIM), a noninvasive technique that we have used successfully to study neurogenic and myopathic atrophy. We performed EIM of the tibialis anterior of 10 subjects with disuse atrophy secondary to cast immobilization and in their contralateral normal leg. Subjects were studied shortly after cast removal and again several weeks to months after the cast was removed and normal mobility was restored. Outpatient neurology and orthopedic practices at a tertiary care medical center. 10 otherwise healthy subjects with unilateral leg fracture. Resistance, reactance, and phase measured at 50 kHz. We found that the main EIM outcome parameter, phase at 50 kHz, was lower in the immobilized leg in 9 of 10 cases. Additionally, when normal mobility was restored, the phase of the casted leg increased relative to its initial measurement in all 10 cases, while it increased inconsistently in the contralateral leg. EIM may be a powerful tool for the assessment of disuse atrophy.
DOI: 10.1002/mus.21075
发表时间: 2008-09
期刊: MUSCLE & NERVE
影响因子: 3.4
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