Transinfection: a method to investigate Wolbachia-host interactions and control arthropod-borne disease.
Transinfection: a method to investigate Wolbachia-host interactions and control arthropod-borne disease.
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DOI：
10.1111/imb.12066
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发表时间：
2014-04
影响因子：
2.6
通讯作者：
Rasgon JL
中科院分区：
文献类型：
--
作者：
Hughes GL;Rasgon JL
细菌内共生菌Wolbachia以多种方式操纵节肢动物宿主生物学，包括性别比例扭曲和后代差异存活。这些细菌感染了大量的节肢动物，其中一些对农业和人类健康构成了严重威胁。沃尔巴克氏菌介导的表型，如细胞质不亲和性和/或病原体干扰，可用于病媒和疾病控制。然而，许多医学上重要的媒介和重要的农业物种没有感染或感染了沃尔巴克氏菌菌株，这些菌株不能产生疾病或害虫控制所需的表型。将沃尔巴克氏菌菌株转移到新宿主(感染)的能力可以创造新的沃尔巴克氏菌与宿主之间的联系。感染有两个主要好处。首先，可以研究沃尔巴克氏菌与宿主的相互作用，以梳理宿主和细菌对表型的影响。其次，沃尔巴克氏菌在特定昆虫体内诱导的所需表型可以转移到另一种受体宿主。这可以允许操纵传播病原体或对农业造成不利影响的昆虫种群。因此，传播感染是探索沃尔巴克氏菌生物学和控制节肢动物传播疾病的宝贵工具。本文对沃尔巴克氏菌的传播方法和应用进行了综述。我们还提供了一份已发表的成功和不成功的沃尔巴克氏菌传播尝试的综合清单。
The bacterial endosymbiont Wolbachia manipulates arthropod host biology in numerous ways including sex ratio distortion and differential offspring survival. These bacteria infect a vast array of arthropods, some of which pose serious agricultural and human health threats. Wolbachia-mediated phenotypes such as cytoplasmic incompatibility and/or pathogen interference can be utilized for vector and disease control. However, many medically important vectors and important agricultural species are uninfected or are infected with strains of Wolbachia that do not elicit phenotypes desirable for disease or pest control. The ability to transfer strains of Wolbachia into new hosts (transinfection) can create novel Wolbachia-host associations. Transinfection has two primary benefits. First, Wolbachia-host interactions can be examined to tease apart the influence of the host and bacteria on phenotypes. Secondly, desirable phenotypes induced by Wolbachia in a particular insect can be transferred to another recipient host. This can allow for manipulation of insect populations that transmit pathogens or detrimentally affect agriculture. As such, transinfection is a valuable tool to explore Wolbachia biology and control arthropod-borne disease. This review summarizes what is currently known about Wolbachia transinfection methods and applications. We also provide a comprehensive list of published successful and unsuccessful Wolbachia transinfection attempts.
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影响因子：
3.7
作者：
Braquart-Varnier C;Lachat M;Herbinière J;Johnson M;Caubet Y;Bouchon D;Sicard M
通讯作者：
Sicard M
影响因子：
3.7
作者：
Chevalier F;Herbinière-Gaboreau J;Bertaux J;Raimond M;Morel F;Bouchon D;Grève P;Braquart-Varnier C
通讯作者：
Braquart-Varnier C
影响因子：
6.7
作者：
Andrews ES;Crain PR;Fu Y;Howe DK;Dobson SL
通讯作者：
Dobson SL
影响因子：
2.1
作者：
Calvitti, Maurizio;Moretti, Riccardo;Dobson, Stephen L.
通讯作者：
Dobson, Stephen L.
DOI：
10.1098/rspb.1998.0402
发表时间：
1998-06-22
影响因子：
4.7
作者：
Bouchon, D;Rigaud, T;Juchault, P
通讯作者：
Juchault, P