Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators.

Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators.
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DOI:
10.3390/ijerph17176117
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发表时间:
2020-08-22
影响因子:
--
通讯作者:
Anderson YC
Anderson YC
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Derraik JGB;Anderson WA;Connelly EA;Anderson YC

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在由SARS-CoV-2引起的COVID-19大流行中,医院经常超出能力。有广泛的报告称,个人防护设备(PPE)供应减少,特别是N95型过滤面罩呼吸器(FFR),这对保护前线医疗/护理人员和尽量减少病毒的进一步传播至关重要。我们进行了一项快速审查,以总结关于SARS-CoV-2的生存能力、关键潜在消毒程序对病毒的有效性(特别是紫外线和热)以及这些程序对FFR性能、材料完整性和/或适合性的影响的现有文献。鉴于SARS-CoV-2的新近发现和有限的相关研究,我们的综述也集中在密切相关的SARS-CoV-1。我们提出了一种可能的整体PPE消毒解决方案,用于潜在的重复使用,可以在许多医疗保健环境中迅速建立,而无需对设备进行重大投资。
In the COVID-19 pandemic caused by SARS-CoV-2, hospitals are often stretched beyond capacity. There are widespread reports of dwindling supplies of personal protective equipment (PPE), particularly N95-type filtering facepiece respirators (FFRs), which are paramount to protect frontline medical/nursing staff, and to minimize further spread of the virus. We carried out a rapid review to summarize the existing literature on the viability of SARS-CoV-2, the efficacy of key potential disinfection procedures against the virus (specifically ultraviolet light and heat), and the impact of these procedures on FFR performance, material integrity, and/or fit. In light of the recent discovery of SARS-CoV-2 and limited associated research, our review also focused on the closely related SARS-CoV-1. We propose a possible whole-of-PPE disinfection solution for potential reuse that could be rapidly instituted in many health care settings, without significant investments in equipment.
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