Prenatal androgen exposure and children's gender-typed behavior and toy and playmate preferences.
Prenatal androgen exposure and children's gender-typed behavior and toy and playmate preferences.
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产前雄激素暴露以及儿童性别类型的行为以及玩具和玩伴的偏好。
DOI：
10.1016/j.yhbeh.2020.104889
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发表时间：
2021-01
影响因子：
3.5
通讯作者：
Hines M
中科院分区：
文献类型：
--
作者：
Spencer D;Pasterski V;Neufeld SAS;Glover V;O'Connor TG;Hindmarsh PC;Hughes IA;Acerini CL;Hines M
我们报告了两项研究的结果，这两项研究调查了产前雄激素暴露与儿童性别类型行为的广泛测量以及儿童玩具和玩伴偏好的可能关系。研究1调查了43名女孩和38名男孩的这些结果，年龄在4至11岁之间，患有先天性肾上腺增生症（CAH，一种导致产前肾上腺雄激素产生增加的遗传疾病），与年龄相似的未受影响的亲属（41名女孩，31名男孩）相比。预测的性别差异被发现的所有结果的措施。此外，与未受影响的女孩相比，CAH女孩表现出男性典型行为和玩具及玩伴偏好增加，女性典型行为和玩具及玩伴偏好减少。研究2调查了羊水睾酮与3至5岁典型发育儿童（48名女孩，44名男孩）的性别类型行为和玩具及玩伴偏好的关系。虽然预测的性别差异，发现所有的结果措施，羊水睾酮是一个显着的相关性，在预测的方向，任何结果措施的性别。研究1的结果为产前雄激素暴露对儿童性别类型行为的影响提供了额外的支持，包括玩具和玩伴偏好。研究2的结果没有，但羊水睾酮可能是一个不够敏感的措施，早期雄激素暴露。在非临床人群中，可能需要一种更敏感和可靠的产前雄激素暴露测量方法来一致地检测与后来性别分型行为的关系。
We report findings from two studies investigating possible relations of prenatal androgen exposure to a broad measure of children’s gender-typed behavior, as well as specifically to children’s toy and playmate preferences. Study 1 investigated these outcomes for 43 girls and 38 boys, aged 4 to 11 years, with congenital adrenal hyperplasia (CAH, a genetic condition causing increased adrenal androgen production beginning prenatally) compared to similarly-aged, unaffected relatives (41 girls, 31 boys). The predicted sex differences were found for all of the outcome measures. Furthermore, girls with CAH showed increased male-typical and decreased female-typical behavior and toy and playmate preferences compared to unaffected girls. Study 2 investigated the relationship of amniotic fluid testosterone to gender-typed behavior and toy and playmate preferences in typically developing children (48 girls, 44 boys) aged 3 to 5 years. Although the predicted sex differences were found for all of the outcome measures, amniotic fluid testosterone was not a significant correlate, in the predicted direction, of any outcome measure for either sex. The results of study 1 provide additional support for an influence of prenatal androgen exposure on children’s gender-typed behavior, including toy and playmate preferences. The results of study 2 do not, but amniotic fluid testosterone may be an insufficiently sensitive measure of early androgen exposure. A more sensitive and reliable measure of prenatal androgen exposure may be needed to consistently detect relations to later gender typed behavior in non-clinical populations.
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影响因子：
3.5
作者：
Bergman, Kristin;Glover, Vivette;Sarkar, Pampa;Abbott, Dave H.;O'Connor, Thomas G.
通讯作者：
O'Connor, Thomas G.
影响因子：
1.5
作者：
Brace, RA
通讯作者：
Brace, RA
DOI：
10.1001/archpedi.1982.03970390032010
发表时间：
1982-01-01
影响因子：
--
作者：
CARSON, DJ;OKUNO, A;MIGEON, CJ
通讯作者：
MIGEON, CJ
影响因子：
3.5
作者：
Arnold AP
通讯作者：
Arnold AP
影响因子：
6.2
作者：
Auyeung B;Ahluwalia J;Thomson L;Taylor K;Hackett G;O'Donnell KJ;Baron-Cohen S
通讯作者：
Baron-Cohen S