Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans.

Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans.
复制标题

DOI:
10.3390/mi7070123
复制
发表时间:
2016-07-19
期刊:
影响因子:
3.4
通讯作者:
Rezai P
Rezai P
中科院分区:
工程技术3区
文献类型:
--
作者:
Gupta BP;Rezai P

文献摘要

参考文献

被引文献

相似文献

线虫是一种小型无脊椎动物,广泛用于与基本生物学过程、疾病模型和药物发现相关的研究。由于它们的体积小,身体透明,这些蠕虫非常适合实验操作。近年来,已经开发了几种微流控设备和平台来加速蠕虫处理、表型研究和筛选。在这里,我们回顾了主要的工具,并简要讨论了它们在线虫研究中的用途。
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies related to fundamental biological processes, disease modelling, and drug discovery. Due to their small size and transparent body, these worms are highly suitable for experimental manipulations. In recent years several microfluidic devices and platforms have been developed to accelerate worm handling, phenotypic studies and screens. Here we review major tools and briefly discuss their usage in C. elegans research.
DOI: 10.3390/mi7070123
发表时间: 2016-07-19
期刊: Micromachines
影响因子: 3.4
作者:
Gupta BP;Rezai P
通讯作者: Rezai P
DOI: 10.1523/jneurosci.0775-07.2007
发表时间: 2007-07-11
影响因子: 5.3
作者:
Gabel, Christopher V.;Gabel, Harrison;Samuel, Aravinthan D. T.
通讯作者: Samuel, Aravinthan D. T.
DOI: 10.1039/c3lc51334c
发表时间: 2014-05-21
期刊: Lab on a chip
影响因子: 6.1
作者:
Ai X;Zhuo W;Liang Q;McGrath PT;Lu H
通讯作者: Lu H
DOI: 10.1098/rstb.2014.0309
发表时间: 2015-04-19
期刊: Philosophical transactions of the Royal Society of London. Series B, Biological sciences
影响因子: --
作者:
Emmons SW
通讯作者: Emmons SW
DOI: 10.1039/c1lc20400a
发表时间: 2011-11-07
期刊: Lab on a chip
影响因子: 6.1
作者:
Chung K;Zhan M;Srinivasan J;Sternberg PW;Gong E;Schroeder FC;Lu H
通讯作者: Lu H