Responses to alcohol and cigarette use during ecologically assessed drinking episodes.
Responses to alcohol and cigarette use during ecologically assessed drinking episodes.
复制标题
DOI：
10.1007/s00213-012-2721-1
复制
发表时间：
2012-10
影响因子：
3.4
通讯作者：
Heath, Andrew C.
中科院分区：
文献类型：
--
作者：
Piasecki, Thomas M.;Wood, Phillip K.;Shiffman, Saul;Sher, Kenneth J.;Heath, Andrew C.
烟草和酒精经常一起使用，这可能部分解释为与共同给药相关的主观效应的独特特征。生态瞬时评估研究已经检验了自然发生的共同使用的影响，但迄今为止，尚未评估随着酒精浓度上升和下降的不同影响。描述在整个现实世界饮酒事件中报告的香烟和酒精影响的主观状态和评估。目前吸烟且经常饮酒的人 (N = 255) 持有电子日记 21 天。分析重点是 2,046 次饮酒事件期间的报告。信号提示在一个情节中喝下第一杯酒后的几个小时内会出现强烈的过采样时刻。使用多级回归分析来预测嗡嗡声、头晕、兴奋和呆滞的评分，作为个人水平和情境协变量、估计血液酒精浓度 (eBAC) 水平、eBAC 上升与下降、吸烟及其相互作用的函数。在此框架内还审查了香烟和酒精影响的评估。酒精和香烟带来的兴奋、兴奋和愉悦是现实世界饮酒事件的显着特征。当 eBAC 较高且下降时，吸烟与嗡嗡声和兴奋感增强有关。吸烟略微增强了女性 eBAC 与饮酒愉悦度评分之间的关系，但男性吸烟则在一定程度上削弱了这种关系。饮酒期间吸烟的部分原因可能是酒精刺激作用在 BAC 峰值之后持续存在。尼古丁和烟草使用对下肢的急性影响值得在实验性酒精挑战研究中进一步审查。
Tobacco and alcohol are frequently used together, and this may be partly explained by a distinct profile of subjective effects associated with co-administration. Ecological Momentary Assessment studies have examined effects of naturally occurring co-use, but, to date, have not assessed differing effects as alcohol levels rise and fall. To describe subjective states and appraisals of cigarette and alcohol effects reported during the entirety of real-world drinking episodes. Currently-smoking frequent drinkers (N = 255) carried electronic diaries for 21 days. Analyses focused on reports made during 2,046 drinking episodes. Signaled prompts intensively oversampled moments in the hours following consumption of the first drink in an episode. Multilevel regression analyses were used to predict ratings of buzz, dizziness, excitement, and sluggishness as a function of person-level and contextual covariates, estimated blood alcohol concentration (eBAC) level, ascending vs. descending eBAC, smoking, and their interactions. Appraisals of cigarette and alcohol effects were also examined within this framework. Buzz, excitement, and pleasure from alcohol and cigarettes were prominent features of real-world drinking episodes. Smoking was associated with enhanced buzz and excitement when eBAC was high and descending. Smoking slightly accentuated the relation between eBAC and ratings of drinking pleasure among women, but this relation was somewhat weakened by smoking among men. Smoking during drinking episodes may be partly be explained by a persistence of stimulant alcohol effects beyond the BAC peak. Acute effects of nicotine and tobacco use on the descending limb deserve further scrutiny in experimental alcohol challenge research.
登录
查看更多内容
影响因子：
3.4
作者：
McKee, Sherry A.;Harrison, Emily L. R.;Shi, Julia
通讯作者：
Shi, Julia
影响因子：
3.4
作者：
PERKINS, KA;SEXTON, JE;STILLER, RL
通讯作者：
STILLER, RL
影响因子：
3.4
作者：
McKee, Sherry A.;O'Malley, Stephanie S.;Krishnan-Sarin, Suchitra
通讯作者：
Krishnan-Sarin, Suchitra
影响因子：
4.7
作者：
McKee, SA;Hinson, R;Petrelli, P
通讯作者：
Petrelli, P
DOI：
10.1111/j.1530-0277.1993.tb00751.x
发表时间：
1993-04-01
影响因子：
3.2
作者：
MARTIN, CS;MOSS, HB
通讯作者：
MOSS, HB