Genetic characterization of the tick-borne orbiviruses.
Genetic characterization of the tick-borne orbiviruses.
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DOI:
10.3390/v7052185
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发表时间:
2015-04-28
期刊:
影响因子:
--
通讯作者:
Mertens PP
中科院分区:
文献类型:
--
作者:
Belaganahalli MN;Maan S;Maan NS;Brownlie J;Tesh R;Attoui H;Mertens PP
The International Committee for Taxonomy of Viruses (ICTV) recognizes four species of tick-borne orbiviruses (TBOs): Chenuda virus, Chobar Gorge virus, Wad Medani virus and Great Island virus (genus Orbivirus, family Reoviridae). Nucleotide (nt) and amino acid (aa) sequence comparisons provide a basis for orbivirus detection and classification, however full genome sequence data were only available for the Great Island virus species. We report representative genome-sequences for the three other TBO species (virus isolates: Chenuda virus (CNUV); Chobar Gorge virus (CGV) and Wad Medani virus (WMV)). Phylogenetic comparisons show that TBOs cluster separately from insect-borne orbiviruses (IBOs). CNUV, CGV, WMV and GIV share low level aa/nt identities with other orbiviruses, in ‘conserved’ Pol, T2 and T13 proteins/genes, identifying them as four distinct virus-species. The TBO genome segment encoding cell attachment, outer capsid protein 1 (OC1), is approximately half the size of the equivalent segment from insect-borne orbiviruses, helping to explain why tick-borne orbiviruses have a ~1 kb smaller genome.
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影响因子:
3.7
作者:
Belaganahalli MN;Maan S;Maan NS;Nomikou K;Pritchard I;Lunt R;Kirkland PD;Attoui H;Brownlie J;Mertens PP
通讯作者:
Mertens PP
影响因子:
3.8
作者:
BORDEN, EC;SHOPE, RE;MURPHY, FA
通讯作者:
MURPHY, FA
影响因子:
5
作者:
Anthony, S. J.;Maan, S.;Mertens, P. P. C.
通讯作者:
Mertens, P. P. C.
影响因子:
2.7
作者:
GUMM, ID;NEWMAN, JFE
通讯作者:
NEWMAN, JFE
影响因子:
3.7
作者:
Anthony, S. J.;Darpel, K. E.;Mertens, P. P. C.
通讯作者:
Mertens, P. P. C.