Visceral organ cross-sensitization - an integrated perspective.
Visceral organ cross-sensitization - an integrated perspective.
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DOI：
10.1016/j.autneu.2009.07.006
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发表时间：
2010-02-16
影响因子：
2.7
通讯作者：
Gebhart, G. F.
中科院分区：
文献类型：
--
作者：
Brumovsky, P. R.;Gebhart, G. F.
关键词：
内脏-躯体转介和致敏已在临床上得到充分记录和广泛研究，而内脏-内脏转介和致敏（称为跨器官致敏）只是最近才受到关注，认为其对内脏疾病状态很重要。由于中枢神经系统中的二级神经元已被广泛地显示为从不同的内脏器官接收会聚输入，因此已经假设跨器官致敏由与内脏-躯体参照和致敏相同的会聚-投射机制产生。然而，越来越多的证据也表明，外围机制的参与，以解释转诊和宣传。我们简要地总结了行为，形态和生理支持，并专注于潜在的机制跨器官敏化。
Viscero-somatic referral and sensitization has been well documented clinically and widely investigated, whereas viscero-visceral referral and sensitization (termed cross-organ sensitization) has only recently received attention as important to visceral disease states. Because second order neurons in the CNS have been extensively shown to receive convergent input from different visceral organs, it has been assumed that cross-organ sensitization arises by the same convergence-projection mechanism as advanced for viscero-somatic referral and sensitization. However, increasing evidence also suggests participation of peripheral mechanisms to explain referral and sensitization. We briefly summarize behavioral, morphological and physiological support of and focus on potential mechanisms underlying cross-organ sensitization.
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影响因子：
2.9
作者：
AMMONS, WS;FOREMAN, RD
通讯作者：
FOREMAN, RD
影响因子：
2.5
作者：
DAWSON, NJ;SCHMID, H;PIERAU, FK
通讯作者：
PIERAU, FK
影响因子：
--
作者：
Asztély, A;Havel, G;Ekström, J
通讯作者：
Ekström, J
影响因子：
1.7
作者：
Chaban, Victor;Christensen, Amy;Micevych, Paul
通讯作者：
Micevych, Paul
DOI：
10.1016/s1071-5576(96)00041-x
发表时间：
1996-11-01
期刊：
JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
影响因子：
--
作者：
Cohen, DP;Ikeda, SR;Lewis, DL
通讯作者：
Lewis, DL