Phenol Concentrations During Childhood and Subsequent Measures of Adiposity Among Young Girls.
Phenol Concentrations During Childhood and Subsequent Measures of Adiposity Among Young Girls.
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DOI：
10.1093/aje/kwx136
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发表时间：
2017-09-01
影响因子：
5
通讯作者：
Teitelbaum SL
中科院分区：
文献类型：
--
作者：
Deierlein AL;Wolff MS;Pajak A;Pinney SM;Windham GC;Galvez MP;Rybak M;Calafat AM;Kushi LH;Biro FM;Teitelbaum SL
Phenolic compounds represent a class of environmental chemicals with potentially endocrine-disrupting capabilities. We investigated longitudinal associations between childhood exposure to phenols, from both manmade and natural sources, and subsequent measures of adiposity among girls enrolled in the Breast Cancer and the Environment Research Program between 2004 and 2007. Baseline (ages 6–8 years) urinary concentrations were obtained for creatinine and phenol metabolites: enterolactone, genistein, daidzein, benzophenone-3, bisphenol A, the sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichlorophenol, and triclosan. Body mass index (weight (kg)/height (m)2), waist circumference, and percent body fat were measured at annual or semiannual examinations through 2015 (n = 1,017). Linear mixed-effects regression was used to estimate how baseline concentrations of phenols (tertile groups) were related to changes in girls’ adiposity measurements from ages 7 through 15 years. Enterolactone was inversely associated with body mass index, waist circumference, and percent body fat, while 2,5-dichlorophenol was positively associated with these measurements. A nonmonotonic association was observed for triclosan and girls’ adiposity; however, it was due to effect modification by baseline overweight status. Triclosan was positively associated with adiposity only among overweight girls. These results suggest that exposure to specific phenols during childhood may influence adiposity through adolescence.
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影响因子：
8
作者：
Biro FM;Galvez MP;Greenspan LC;Succop PA;Vangeepuram N;Pinney SM;Teitelbaum S;Windham GC;Kushi LH;Wolff MS
通讯作者：
Wolff MS
影响因子：
5.8
作者：
Croes, K.;Den Hond, E.;Baeyens, W.
通讯作者：
Baeyens, W.
影响因子：
--
作者：
La Merrill, Michele;Birnbaum, Linda S.
通讯作者：
Birnbaum, Linda S.
Chamacos队列中儿童期的产前和产后双酚A暴露和体重指数。
影响因子：
10.4
作者：
Harley KG;Aguilar Schall R;Chevrier J;Tyler K;Aguirre H;Bradman A;Holland NT;Lustig RH;Calafat AM;Eskenazi B
通讯作者：
Eskenazi B
影响因子：
10.4
作者：
Braun JM;Lanphear BP;Calafat AM;Deria S;Khoury J;Howe CJ;Venners SA
通讯作者：
Venners SA