Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview.
Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview.
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DOI：
10.3390/nano8090681
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发表时间：
2018-08-31
期刊：
影响因子：
--
通讯作者：
Andronescu E
中科院分区：
文献类型：
--
作者：
Burdușel AC;Gherasim O;Grumezescu AM;Mogoantă L;Ficai A;Andronescu E
在过去的几年中，银纳米粒子（AgNPs）成为最受研究和探索的纳米技术衍生的纳米结构之一，因为纳米银基材料被证明具有有趣的，具有挑战性的，和有前途的特性，适合于各种生物医学应用。在AgNPs的现代生物医学潜力中，巨大的兴趣是面向治疗增强的个性化医疗实践。事实证明，AgNPs具有真正的功能和令人印象深刻的潜力，可用于开发新型抗菌剂，药物递送制剂，检测和诊断平台，生物材料和医疗器械涂层，组织修复和再生材料，复杂的医疗保健条件策略和性能增强的治疗替代品。鉴于银纳米颗粒在生物医学方面的潜在应用，人们在了解其生物相互作用的复杂机制和可能的毒性作用方面做出了令人印象深刻的努力。在这篇综述中，我们集中在最新的数据有关的AgNP基纳米结构的生物医学用途，包括其潜在的毒性，独特的理化性质，和生物功能行为，在此讨论内在的抗炎，抗菌，抗病毒和抗真菌活性的银基纳米结构。
During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures.
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影响因子：
10.7
作者：
Akter M;Sikder MT;Rahman MM;Ullah AKMA;Hossain KFB;Banik S;Hosokawa T;Saito T;Kurasaki M
通讯作者：
Kurasaki M
DOI：
10.1016/j.nano.2017.11.006
发表时间：
2018-02-01
影响因子：
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作者：
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通讯作者：
Walch, Michael
DOI：
10.1016/j.msec.2012.07.006
发表时间：
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影响因子：
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作者：
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6.8
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影响因子：
4.9
作者：
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