Functional Architecture of Motion Direction in the Mouse Superior Colliculus.

Functional Architecture of Motion Direction in the Mouse Superior Colliculus.
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DOI:
10.1016/j.cub.2020.06.023
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发表时间:
2020-09-07
期刊:
Current biology : CB
影响因子:
--
通讯作者:
Meister M
Meister M
中科院分区:
其他
文献类型:
--
作者:
Li YT;Turan Z;Meister M

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Motion vision is important in guiding animal behavior. Both the retina and the visual cortex process object motion in largely unbiased fashion: all directions are represented at all locations in the visual field. We investigate motion processing in the superior colliculus of the awake mouse, by optically recording neural responses across both hemispheres. Within the retinotopic map, one finds large regions of ~500 μm size where neurons prefer the same direction of motion. This preference is maintained in depth to ~350 μm. The scale of these patches, ~30 degrees of visual angle, is much coarser than the animal’s visual resolution (~2 degrees). A global map of motion direction shows approximate symmetry between the left and right hemispheres and a net bias for upward-nasal motion in the upper visual field. Li et al. investigate the functional architecture of visual motion direction in the superior colliculus of awake mice. Using two-photon and wide-field microscopy they explore most of the visual field, revealing a patchy organization: In small regions, measuring ~30 degrees across, neurons are all biased for the same direction of motion.
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