Macular thickness by age and gender in healthy eyes using spectral domain optical coherence tomography.
Macular thickness by age and gender in healthy eyes using spectral domain optical coherence tomography.
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DOI：
10.1371/journal.pone.0037638
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Adhi MI
中科院分区：
文献类型：
--
作者：
Adhi M;Aziz S;Muhammad K;Adhi MI
采用光谱域光学相干断层扫描（SD-OCT）确定健康眼正常黄斑厚度及其随年龄和性别的变化。在这项横断面分析中，在陶氏健康科学大学眼科和巴基斯坦卡拉奇民用医院，使用Topcon SD-OCT系统对220名健康受试者的220只眼睛进行光栅扫描。记录每例受试者ETDRS图所有9个区域的黄斑厚度。黄斑厚度测量的变化，年龄和性别进行了测定。220例受试者的平均年龄为45.3岁（16-80岁）。使用ETDRS图，测量所有受试者的中心凹厚度为229±20.46 µm。所有受试者的平均黄斑厚度为262.8±13.34 µm。与女性相比，男性与更大的中央凹（p<0.0001）和平均黄斑（p<0.0001）厚度相关。平均黄斑厚度（r2 = 0.01; p>0.05）和中心凹厚度（r2 = 0.00004; p>0.05）与年龄无关。 我们使用Topcon SD-OCT系统提供了黄斑厚度的标准数据。我们的结果与使用类似OCT系统的一些报告相当，并且与其他报告不同。我们的研究结果表明，男性与较大的黄斑厚度，而黄斑厚度与年龄在健康的眼睛没有关联。这是巴基斯坦的第一个黄斑厚度的标准数据;诊断和监测黄斑病变的基准。本研究中获得的值可能有助于与其他人群、其他SD-OCT系统和未来成像技术进行比较。
To determine normal macular thickness and its variation by age and gender in healthy eyes using spectral-domain optical coherence tomography (SD-OCT). In this cross-sectional analysis, two hundred and twenty eyes of 220 healthy subjects underwent raster scanning using Topcon SD-OCT system, at the Department of Ophthalmology, Dow University of Health Sciences and Civil Hospital Karachi, Pakistan. Macular thickness from all 9 regions of the ETDRS map was documented for each subject. Variations in macular thickness measurements by age and gender were determined. The 220 subjects had a mean age of 45.3 years (16–80 years). Using the ETDRS map, foveal thickness for all subjects was measured to be 229±20.46 µm. Mean macular thickness for all subjects was 262.8±13.34 µm. Male gender was associated with greater foveal (p<0.0001) and mean macular (p<0.0001) thickness compared to females. There was no association of mean macular thickness (r2 = 0.01; p>0.05) and foveal thickness (r2 = 0.00004; p>0.05) with age. We have provided normative data for macular thickness using Topcon SD-OCT system. Our results are comparable to some and vary from other reports using the similar OCT system. Our results suggest that male gender is associated with greater macular thickness, while macular thickness has no association with age in healthy eyes. This is the first normative data for macular thickness from Pakistan; benchmark for diagnosing and monitoring macular pathologies. The values obtained in this study may be useful for comparison with other populations, other SD-OCT systems and future imaging technologies.
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影响因子：
--
作者：
Chan, A;Duker, JS;Schuman, JS
通讯作者：
Schuman, JS
影响因子：
4.2
作者：
Kashani, Amir H.;Zimmer-Galler, Ingrid E.;Shah, Syed Mahmood;Dustin, Laurie;Do, Diana V.;Eliott, Dean;Haller, Julia A.;Nguyen, Quan Dong
通讯作者：
Nguyen, Quan Dong
DOI：
10.1097/iae.0b013e3181bd2c3b
发表时间：
2010-02
期刊：
Retina (Philadelphia, Pa.)
影响因子：
--
作者：
Sull AC;Vuong LN;Price LL;Srinivasan VJ;Gorczynska I;Fujimoto JG;Schuman JS;Duker JS
通讯作者：
Duker JS
DOI：
10.2174/1874364100903010010
发表时间：
2009-04-20
期刊：
The open ophthalmology journal
影响因子：
--
作者：
Bruce A;Pacey IE;Dharni P;Scally AJ;Barrett BT
通讯作者：
Barrett BT
影响因子：
4.4
作者：
Song, Won Kyung;Lee, Sung Chul;Kim, Sung Soo
通讯作者：
Kim, Sung Soo