In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances
In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances
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不同交联辐照度下光学相干弹性成像对角膜生物力学特性的体内评估
DOI:
10.1117/1.jbo.24.10.105001
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发表时间:
2019-10
影响因子:
3.5
通讯作者:
Dexi Zhu
中科院分区:
文献类型:
--
作者:
Yuheng Zhou;Yuanyuan Wang;Meixiao Shen;Zi Jin;Yihong Chen;Yue Zhou;Jia Qu;Dexi Zhu
Abstract. Corneal collagen cross-linking (CXL) strengthens the biomechanical properties of damaged corneas. Quantifying the changes of stiffness due to different CXL protocols is difficult, especially in vivo. A noninvasive elastic wave-based optical coherence elastography system was developed to construct in vivo corneal elasticity maps by excitation of air puff. Biomechanical differences were compared for rabbit corneas given three different CXL protocols while keeping the total energy delivered constant. The Young’s modulus was weaker in corneas treated with higher irradiance levels over shorter durations, and a slight increase of Young’s modulus was present in all groups one week after the recovery process. Due to the noninvasive nature and minimal force to generate corneal elastic waves, this technique has the potential for early detection and treatment of corneal diseases in clinic.
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影响因子:
2.4
作者:
Tao, Chen;Han, Zhaolong;Ren, Qiushi
通讯作者:
Ren, Qiushi
DOI:
10.1007/s00417-011-1897-0
发表时间:
2012-04-01
影响因子:
2.7
作者:
Gkika, Maria;Labiris, Georgios;Kozobolis, Vassilios
通讯作者:
Kozobolis, Vassilios
DOI:
10.1109/tbme.2018.2853571
发表时间:
2019-03
期刊:
IEEE transactions on bio-medical engineering
影响因子:
--
作者:
Qian X;Ma T;Shih CC;Heur M;Zhang J;Shung KK;Varma R;Humayun MS;Zhou Q
通讯作者:
Zhou Q
影响因子:
3.5
作者:
Song, Shaozhen;Huang, Zhihong;Wang, Ruikang K.
通讯作者:
Wang, Ruikang K.
影响因子:
3.4
作者:
Shang Wang;K. Larin
通讯作者:
Shang Wang;K. Larin