Spatial and Environmental Variation of the Human Hair Microbiota.

Spatial and Environmental Variation of the Human Hair Microbiota.
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DOI:
10.1038/s41598-018-27100-1
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发表时间:
2018-06-13
期刊:
影响因子:
4.6
通讯作者:
Nelson KE
Nelson KE
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Brinkac L;Clarke TH;Singh H;Greco C;Gomez A;Torralba MG;Frank B;Nelson KE

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皮肤是一个复杂的生态系统,拥有多种微生物群落。其高度可变的特性和内在和外在因素的影响创造了独特的微环境,使特定的微生物茁壮成长。作为皮肤的一部分,头发支持自己的微生物栖息地,这也是个人内部和个人之间的变量。由于在个体身上可以获得独特的特征,这种很少被探索的基质在法医微生物组研究中具有重大潜力。为了进一步研究这一点,我们研究了健康成人头皮和阴部的头发微生物群,以研究毛干微环境的微生物变化。我们的研究结果表明,在来自身体不同部位的毛干上鉴定的微生物群落之间存在明显差异。来自不同毛发来源的群落的分类组成与来自其相关皮肤区域的群落最相似。我们进一步证明,头发微生物群因地理来源而异,并有可能用于预测头发的来源位置。
The skin is a complex living ecosystem harboring diverse microbial communities. Its highly variable properties and influence of intrinsic and extrinsic factors creates unique microenvironments where niche-specific microbes thrive. As part of the skin, hair supports its own microbial habitat that is also intra and inter-personal variable. This little explored substrate has significant potential in forensics microbiome research due to the unique signatures that are available on an individual. To further investigate this, we explored the hair microbiota from scalp and pubic regions in healthy adults to investigate how the hair shaft microenvironment varies microbially. Our results suggest that there are distinct differences between the microbial communities identified on hair shafts originating from different parts of the body. The taxonomic composition of the communities from different hair sources are most reminiscent of those identified from their associated cutaneous region. We further demonstrate that the hair microbiota varies by geographical origin and has the potential to be used to predict the source location of the hair.
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