Enhancement of Biocompatibility of Fish Scale-Based Hydroxyapatite-Infused Fibrous Scaffolds by Low-Temperature Plasma
Enhancement of Biocompatibility of Fish Scale-Based Hydroxyapatite-Infused Fibrous Scaffolds by Low-Temperature Plasma
复制标题
低温等离子体增强鱼鳞羟基磷灰石纤维支架的生物相容性
DOI：
10.1007/s11837-023-05750-5
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发表时间：
2023
期刊：
影响因子：
2.6
通讯作者：
Rangari, Vijaya K.
中科院分区：
文献类型：
--
作者：
Kodali, Deepa;Mohammed, Zaheeruddin;Gunturu, Dilip Reddy;Samuel, Temesgen;Jeelani, Shaik;Rangari, Vijaya K.
羟基磷灰石(HAP)具有良好的促进细胞生长和增殖的能力，作为一种极具价值的生物材料受到了极大的关注。海洋环境的副产品，特别是鱼鳞，已被证明是HAP的重要来源。尽管如此，羟基磷灰石仍然对生物医学应用的基质具有深远的影响。本研究采用强制纺丝法制备了鱼鳞衍生纳米羟基磷灰石(n-HAP) = /非织造聚己内酯纤维支架。通过氧等离子体处理对纳米纤维支架的表面性质进行了改性，并研究了它们对n-HAP注入的PCL支架表面性能的影响。等离子体处理有利于2wt.%和3wt.%的高O/C比和高C/O含量的支架材料，并具有较高的细胞生长率。3wt.%的支架具有很高的结晶度，是纯纤维结晶度的两倍。经等离子体处理的2wt.%和3wt.%支架具有较高的细胞生长率，几乎是纯支架的两倍，这与X射线光电子能谱(XPS)的结果一致。等离子体处理提高了含有2和3wt.%n-HAP的纤维支架的功能性能和生物相容性。
Owing to its excellent ability to enhance the cell growth and proliferation, hydroxyapatite (HAp) has received tremendous attention as a highly valuable biomaterials. Byproducts from the marine environment, especially fish scales, have proved to be a vital source for HAp. Nevertheless, HAp still has a profound influence on the matrices designed for biomedical applications. In this study, fish scale-derived nano-hydroxyapatite (n-HAp) = infused non-woven polycaprolactone (PCL) fibrous scaffolds are developed byforce spinning. The surface properties of the nanofibrous scaffolds are modified by oxygen plasma treatment, and their influence on n-HAP-infused PCL scaffolds is investigated. Plasma treatment is favorable for 2 wt.% and 3 wt.% scaffolds with a high O/C ratio and improving C=O content, and are found to have high cell growth. The 3 wt.% scaffolds have high crystallinity which is twice the crystallinity of neat fibers. The plasma treated 2 wt.% and 3 wt.% scaffolds were found to have high cell growth almost twice that of neat scaffolds, and these observations complied with the results from x-ray photoelectron spectroscopy (XPS). The plasma treatment enhances the functional properties and biocompatibility of fibrous scaffolds containing 2 and 3 wt.% n-HAP.
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影响因子：
4.1
作者：
Cheng, Qian;Lee, Benjamin Li-Ping;Li, Song
通讯作者：
Li, Song
DOI：
10.1016/j.jmrt.2020.09.093
发表时间：
2020-11-01
影响因子：
6.4
作者：
Hembrick-Holloman, Vincent;Samuel, Temesgen;Rangari, Vijaya K.
通讯作者：
Rangari, Vijaya K.
用于骨组织工程的 3D 打印壳聚糖/明胶/羟基磷灰石支架的氧等离子体处理。
影响因子：
--
作者：
Chang;S. Yang;Sang‐Chul Jung;Byung
通讯作者：
Byung
通过旋转喷射纺丝和静电纺丝获得纤维状 PCL/PLLA 支架
DOI：
--
发表时间：
2018
期刊：
影响因子：
--
作者：
Talita A. Vida;A. Motta;A. R. Santos;G. C. Cardoso;C. Brito;C. Zavaglia
通讯作者：
C. Zavaglia
影响因子：
3.5
作者：
Prabhakaran, Molamma P.;Venugopal, J.;Ramakrishna, S.
通讯作者：
Ramakrishna, S.