Identification of myb genes in Euplotes aediculatus may indicate an early evolutionary process.

Identification of myb genes in Euplotes aediculatus may indicate an early evolutionary process.
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幼虫 myb 基因的鉴定可能表明早期的进化过程。

DOI:
10.1016/j.gene.2013.06.072
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发表时间:
2013-11
期刊:
影响因子:
3.5
通讯作者:
Chen, Quan
Chen, Quan
中科院分区:
生物学3区
文献类型:
--
作者:
Lv, Jianhua;Yang, Tie;Yang, Haixia;Li, Zhiwei;Qin, Peiwu;Zhang, Xiling;Liang, Xiaoliang;Li, Jiayin;Chen, Quan

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钼基因家族编码的蛋白质具有高度保守的DNA结合域,具有转录调节功能。在动物中有三个具有三个Myb基序重复的钼基因,即c-myb、A-myb和B-myb。相比之下,植物拥有丰富的霉菌基因,其中大部分是R2R3型(有两个Myb基序)。很少有植物真菌基因是R1R2R3型的。最近通过简并聚合酶链式反应发现了游离体中的5个新的myb成员,这表明Mo基因在单细胞原生体界中也是一个多成员家族,与其他多细胞真核生物一样。整个基因家族进一步表明R1R2R3-和R2R3-型肌均存在。系统发育分析为霉菌基因的进化提供了具体的新证据。
Themybgene family encodes proteins characterized by a highly conserved DNA-binding domain and functions as transcription regulators. There are threemybgenes in animals with three Myb-motif repeats, namely c-myb, A-myb, and B-myb. By contrast, plants possess an abundance ofmybgenes, the majority of which are of the type R2R3 (with two Myb-motifs). Few plantmybgenes are of the type R1R2R3. Five newmybmembers in Euplotes were recently identified through degenerate polymerase chain reaction, which suggests that themybgene is also a multi-member family in the unicellular protist kingdom as in other multi-cellular eukaryotes. The entire gene family further shows the presence of both R1R2R3- and R2R3-typemyb. The phylogenic analysis provides concrete new evidence for the evolution ofmybgenes.
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