Effects of age and sex on retention of mercury by methyl mercury-treated rats.
Effects of age and sex on retention of mercury by methyl mercury-treated rats.
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年龄和性别对甲基汞治疗大鼠汞保留的影响。
DOI：
10.1016/0041-008x(82)90145-4
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发表时间：
1982
影响因子：
3.8
通讯作者：
Mushak,P
中科院分区：
文献类型：
--
作者：
Thomas,DJ;Fisher,HL;Hall,LL;Mushak,P
Male and female Long Evans rats 7, 15, 20, 24, or 56 days old received a single subcutaneous injection of 1 μmol of methyl mercury-203/kg and the whole body retention of radiomercury was determined for up to 139 days thereafter. For rats dosed at 7 or 15 days of age, whole body clearance of mercury was extremely slow until animals reached 17 to 18 days of age. Subsequent excretion was monoexponential in the 7-day-old group and biexponential in the 15-day-old group. For rats dosed at 20, 24, or 56 days of age, onset of excretion was immediate and the pattern of clearance was biexponential. In rats dosed at 56 days of age, the retention of mercury by the average male and average female was significantly different (p = 0.001). No sexual difference in the estimate of whole body retention of mercury was seen in the other age groups. The presence of an interval of very slow excretion of mercury in young rats and the subsequent slower excretion of mercury in these animals than in rats dosed with methyl mercury later in life suggest that increased hazards of methyl mercury exposure in early life may be related to increased retention of the organomercurial or inorganic Hg.
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203Hg在孕鼠和胎鼠中的分布
DOI：
10.1002/tera.1420130306
发表时间：
1976
期刊：
Teratology
影响因子：
--
作者：
R. B. King;M. Robkin;T. Shepard
通讯作者：
T. Shepard
二巯基丁二酸对大鼠甲基汞中毒的暴露后预防性治疗。
影响因子：
3.8
作者：
L. Magos;G. C. Peristianis;R. Snowden
通讯作者：
R. Snowden
温度等因素对甲基汞对小鼠毒性的影响。
影响因子：
3.8
作者：
K. Nomiyama;K. Matsui;H. Nomiyama
通讯作者：
H. Nomiyama
甲基汞在怀孕、未怀孕和胎儿大鼠大脑中的积累。
DOI：
10.1016/0024-3205(73)90028-3
发表时间：
1973
期刊：
Life sciences. Pt. 2: Biochemistry, general and molecular biology
影响因子：
--
作者：
David H. Null;Peter S. Gartside;Edward T. Wei
通讯作者：
Edward T. Wei
年龄对大鼠全身 115m Cd 保留和分布的影响。
影响因子：
8.3
作者：
D. Kello;K. Kostial
通讯作者：
K. Kostial