Iron Nutriture of the Fetus, Neonate, Infant, and Child.
Iron Nutriture of the Fetus, Neonate, Infant, and Child.
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DOI：
10.1159/000481447
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发表时间：
2017
影响因子：
3.9
通讯作者：
Cerami C
中科院分区：
文献类型：
--
作者：
Cerami C
铁是一种关键的营养物质，对发育中的胎儿、新生儿、婴儿和儿童都是必不可少的。在生命的早期阶段，铁的需求量很高，因为它对新的红细胞和肌肉细胞的产生以及大脑的发育至关重要。新生儿、婴儿和儿童从饮食来源获得铁，包括母乳(乳铁蛋白)以及含血红素和不含血红素的食物。缺铁是全世界儿童和孕妇最常见的微量营养素缺乏症。缺铁性贫血和缺铁性贫血会影响发育中儿童的生长和能量水平以及运动和认知能力。胎儿完全依赖母亲通过胎盘传递的铁，尽管通常在出生时对缺铁有很好的保护，但母亲的缺铁性贫血可能会增加其孩子早在4个月时患缺铁和缺铁缺乏症的风险。这篇综述将讨论铁的用途，铁的需求，以及从怀孕到儿童时期的铁的来源。此外，它还将描述儿童缺铁性贫血和缺铁性贫血的患病率和临床表现，并讨论儿童和孕妇补铁的建议。
Iron is a key nutrient and is essential for the developing fetus, neonate, infant, and child. Iron requirements are high during early stages of life because it is critically important for the production of new red blood cells and muscle cells as well as brain development. Neonates, infants, and children obtain iron from dietary sources including breast milk (lactoferrin) and heme- and non-heme-containing foods. Iron deficiency (ID) is the most common micronutrient deficiency in children and pregnant women worldwide. ID and iron deficiency anemia (IDA) can affect growth and energy levels as well as motor and cognitive performance in the developing child. The fetus is completely dependent on maternal iron crossing through the placenta and, although it is generally well protected against deficiency at birth, ID in mothers can increase the risk of ID and IDA in their children as early as 4 months. This review will discuss the uses of iron, iron requirements, and the sources of iron from conception through childhood. In addition, it will describe the prevalence and clinical manifestations of ID and IDA in children and discuss recommendations for iron supplementation of children and pregnant women.
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DOI：
10.1016/j.jpeds.2016.05.013
发表时间：
2016-08
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Cusick SE;Georgieff MK
通讯作者：
Georgieff MK
DOI：
10.1530/rep-14-0053
发表时间：
2014-09
期刊：
Reproduction (Cambridge, England)
影响因子：
--
作者：
Cao C;Pressman EK;Cooper EM;Guillet R;Westerman M;O'Brien KO
通讯作者：
O'Brien KO
DOI：
10.1016/j.jpeds.2015.08.035
发表时间：
2015-12
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Geng F;Mai X;Zhan J;Xu L;Zhao Z;Georgieff M;Shao J;Lozoff B
通讯作者：
Lozoff B
影响因子：
8
作者：
Burden, Matthew J.;Westerlund, Alissa J.;Jacobson, Joseph L.
通讯作者：
Jacobson, Joseph L.
影响因子：
7.1
作者：
Allen, LH
通讯作者：
Allen, LH