Micro- and nanotechnologies for intelligent and responsive biomaterial-based medical systems.
Micro- and nanotechnologies for intelligent and responsive biomaterial-based medical systems.
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DOI：
10.1016/j.addr.2009.09.002
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发表时间：
2009-12-17
影响因子：
16.1
通讯作者：
Peppas, Nicholas A.
中科院分区：
文献类型：
--
作者：
Caldorera-Moore, Mary;Peppas, Nicholas A.
关键词：
在各种病理生理学疾病的医疗治疗方面的进步要求开发更好的治疗剂，以及将所需的治疗剂与可用作传感器和载体的设备集成生物材料相结合。将微米和纳米复合系统与具有感知和响应能力的智能生物材料相结合，是开发更好的诊断和治疗医疗系统的一条很有前途的途径。微纳机电系统(MEMS和NEMS)现在正在成为一系列潜在的强大的新技术，用于药物输送、诊断工具和组织工程。微米和纳米制造技术的进步提高了为许多病理生理应用创造性能更好的治疗系统的能力。更重要的是，基于MEMS和NEMS的组织再生支架、生物传感器和药物输送设备为模拟生物系统的自然智能和响应提供了新的机会。
Advances in medical treatments of a wide variety of pathophysiological conditions require the development of better therapeutic agents, as well as a combination of the required therapeutic agents with device-integrated biomaterials that can serve as sensors and carriers. Combination of micro- and nanofabricated systems with intelligent biomaterials that have the ability to sense and respond is a promising avenue for the development of better diagnostic and therapeutic medical systems. Micro- and nano-electromechanical systems (MEMs and NEMs) are now becoming a family of potentially powerful new technologies for drug delivery, diagnostic tools, and tissue engineering. Improvements in micro- and nano-fabrication technology have enhanced the ability to create better performing therapeutic systems for numerous pathophysiological applications. More importantly, MEMS and NEMS-based tissue regeneration scaffolds, biosensors, and drug delivery devices provide new opportunities to mimic the natural intelligence and response of biological systems.
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影响因子：
10.8
作者：
Anseth, KS;Metters, AT;Bowman, CN
通讯作者：
Bowman, CN
影响因子：
10.8
作者：
Ahmed, A;Bonner, C;Desai, TA
通讯作者：
Desai, TA
DOI：
10.1073/pnas.192291499
发表时间：
2002-09-17
影响因子：
11.1
作者：
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通讯作者：
Mooney, DJ
影响因子：
14
作者：
Akala, EO;Kopecková, P;Kopecek, J
通讯作者：
Kopecek, J
影响因子：
2.3
作者：
Bender, M;Otto, M;Kurz, H
通讯作者：
Kurz, H