Nutritional Factors in Occupational Lung Disease.
Nutritional Factors in Occupational Lung Disease.
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DOI：
10.1007/s11882-021-01003-0
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发表时间：
2021-03-25
影响因子：
5.5
通讯作者：
Hanson C
中科院分区：
文献类型：
--
作者：
Isaak M;Ulu A;Osunde A;Nordgren TM;Hanson C
哮喘和慢性阻塞性肺病等肺部疾病是主要的公共卫生问题，与职业暴露有关。虽然限制这些疾病发展和进展的疗法有限，但营养干预可以提供潜在的替代方案来介导与这些疾病相关的炎症。这是一个叙述性审查的相关营养素的炎症和呼吸结果与职业暴露的现状。近年来研究的相关营养素包括omega-3多不饱和脂肪酸、锌、维生素D、乳制品和抗氧化剂。这些营养素已被证明有可能预防或改变与职业暴露相关的不良后果，主要是在临床前研究中。目前与职业暴露相关的呼吸后果的治疗方法是有限的;因此，解决减少炎症的策略对于改善生活质量和限制医疗保健成本非常重要。需要更多的人体研究来确定营养作为干预措施的有效性。
Lung diseases such as asthma and COPD are major public health issues and related to occupational exposures. While therapies to limit the development and progression of these diseases are limited, nutrition interventions could offer potential alternatives to mediate the inflammation associated with these diseases. This is a narrative review of the current state of relevant nutrients on inflammation and respiratory outcomes associated with occupational exposures. Relevant nutrients that have been investigated in recent years include omega-3 polyunsaturated fatty acids, zinc, vitamin D, dairy products, and antioxidants. These nutrients have demonstrated the potential to prevent or modify the adverse outcomes associated with occupational exposures, primarily in preclinical studies. Current therapies for respiratory consequences associated with occupational exposures are limited; therefore, addressing strategies for reducing inflammation is important in improving quality of life and limiting health care costs. More human studies are warranted to determine the effectiveness of nutrition as an intervention.
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发表时间：
2010-12
期刊：
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影响因子：
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