Self-collection of hair samples during the COVID-19 pandemic.

Self-collection of hair samples during the COVID-19 pandemic.
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DOI:
10.1016/j.cpnec.2022.100156
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发表时间:
2022-11
影响因子:
--
通讯作者:
Shi, Sophie
Shi, Sophie
中科院分区:
其他
文献类型:
--
作者:
Toly, Valerie Boebel;Fiala, Marisa;Shi, Sophie

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由于COVID-19大流行,实施了公共卫生限制,要求我们对头发皮质醇样本的采集从亲自采集到自我采集进行研究方案修订。目的是描述从亲自毛发皮质醇样本采集到使用书面和视频说明的参与者自我采集的方案过渡过程以及该过渡的可接受性和可行性。方案转换需要修订书面说明,并链接到新开发的毛发样本自我采集视频。在最初的参与者同意提供头发样本之间的人(79/114; 69.3%)与自我收集(254/417; 60.9%)协议方法的差异不大。一些参与者最初对提供自我采集的毛发样本犹豫不决,但评论说自我采集比他们预期的更容易,这支持了该方案变更的可接受性。然而,关于可行性,16.8%的参与者自行采集的头发样本没有被研究工作人员收到,尽管有提醒(14.3%)或邮件递送或退回问题(2.5%)。我们的头发样本收集方案从亲自到自我收集的过渡是可以接受的和可行的。以各种形式(口头、书面、视频)提供毛发样本自我采集的说明有助于减少有关过程的不确定性和犹豫,并促进参与者之间的一致性。此外,持续的后续沟通是及时收到参与者头发样本的关键。首个毛发自我采集方案,用于评估COVID-19大流行期间的皮质醇。自行采集头发样本进行皮质醇分析是可以接受和可行的。多种指令传递模式(口头,书面,视频)帮助头发自我收集。预先计划,及时与参与者联系,提高头发自我收集的回报率。
Due to the COVID-19 Pandemic, public health restrictions were implemented that required study protocol revisions for our collection of hair cortisol samples from in-person to self-collection. The purpose is to provide descriptions of the protocol transition process from in-person hair cortisol sample collection to participant self-collection using written and video instructions as well as the acceptability and feasibility of this transition. The protocol transition required revisions to the written instructions with a link to a newly developed video for hair sample self-collection. There was little difference in the initial participant agreement to provide a hair sample between in-person (79/114; 69.3%) versus self-collection (254/417; 60.9%) protocol methods. Some participants were initially hesitant to provide a self-collected hair sample but commented that self-collection was easier than they anticipated which supports the acceptability of this protocol change. However, regarding feasibility, 16.8% of participant self-collected hair samples were not received by study staff despite reminders (14.3%) or there was an issue with mail delivery or return (2.5%). The transition of our hair sample collection protocol from in-person to self-collection was acceptable and feasible. Providing instructions for hair sample self-collection in a variety of formats (oral, written, video) helped to decrease uncertainty and hesitancy regarding the process and promote agreement among participants. In addition, consistent follow-up communication was key to timely receipt of the hair samples from participants. First hair self-collection protocol to assess cortisol during the COVID-19 Pandemic. Hair sample self-collection for cortisol analysis is acceptable and feasible. Multiple instruction delivery modes (oral, written, video) aid hair self-collection. Pre-planned, timely contact with participants boosts hair self-collection return rate.
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