Promising Roles of Alternative Medicine and Plant-Based Nanotechnology as Remedies for Urinary Tract Infections.
Promising Roles of Alternative Medicine and Plant-Based Nanotechnology as Remedies for Urinary Tract Infections.
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DOI：
10.3390/molecules25235593
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发表时间：
2020-11-28
期刊：
影响因子：
--
通讯作者：
Bungau S
中科院分区：
文献类型：
--
作者：
Chandra H;Singh C;Kumari P;Yadav S;Mishra AP;Laishevtcev A;Brisc C;Brisc MC;Munteanu MA;Bungau S
尿路感染（UTI）被认为是全球最常见的感染，女性的发病率为40 - 60%。此外，成年女性中这种疾病的患病率是男性的30倍。UTI通常在许多医院和临床实践中发现;作为疾病，它们是复杂的和简单的;在简单的情况下，泌尿生殖道没有结构或功能异常。然而，梗阻、尿流滞留和导管的使用增加了复杂性。有几种细菌（例如，E.大肠杆菌、肺炎克雷伯氏菌、普通变形杆菌等）成功地居住在城市里。诊断不仅要准确，而且要快速，因此早期检测是控制尿路病原体引起的尿路感染的重要步骤。UTI的治疗包括适当的抗菌治疗，以控制感染并杀死体内的致病微生物。抗生素的长期使用导致了多药耐药性，从而阻碍了治疗。因此，替代的组合药物方法带来了一些希望。可用的治疗被认为是顺势疗法，阿育吠陀，Unani和其他草药药物。纳米颗粒在对抗UTI方面即将发挥新的作用，需要进一步验证。基于药用植物的纳米技术方法的作用已经显示出有希望的结果。因此，必须积极研究以植物为基础的UTI疗法，如阿育吠陀生物学。
Urinary tract infections (UTIs) are considered to be the most common infections worldwide, having an incidence rate of 40−60% in women. Moreover, the prevalence of this disorder in adult women is 30 times more than in men. UTIs are usually found in many hospitals and clinical practice; as disorders, they are complicated and uncomplicated; in uncomplicated cases, there is no structural or functional abnormality in the urogenital tract. However, obstruction, retention of urine flow and use of catheters increase the complexity. There are several bacteria (e.g., E. coli, Klebsiella pneumoniae, Proteus vulgaris, etc.) successfully residing in the tract. The diagnosis must not only be accurate but rapid, so early detection is an important step in the control of UTIs caused by uropathogens. The treatment of UTIs includes appropriate antimicrobial therapy to control the infection and kill the causal microbes inside the body. A long-time usage of antibiotics has resulted in multidrug resistance causing an impediment in treatment. Thus, alternative, combinatorial medication approaches have given some hope. Available treatments considered Homeopathic, Ayurvedic, Unani, and other herbal-based drugs. There are new upcoming roles of nanoparticles in combating UTIs which needs further validation. The role of medicinal plant-based nanotechnology approaches has shown promising results. Therefore, there must be active research in phyto-based therapies of UTIs, such as Ayurvedic Biology.
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