The effect of gamma tACS over the M1 region and cerebellar hemisphere does not depend on current intensity
The effect of gamma tACS over the M1 region and cerebellar hemisphere does not depend on current intensity
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伽玛 tACS 对 M1 区域和小脑半球的影响不依赖于电流强度
DOI：
10.1016/j.jocn.2019.03.045
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发表时间：
2019
影响因子：
2
通讯作者：
Onishi Hideaki
中科院分区：
文献类型：
--
作者：
Miyaguchi Shota;Otsuru Naofumi;Kojima Sho;Yokota Hirotake;Saito Kei;Inukai Yasuto;Onishi Hideaki
经颅交流电刺激（tACS）已被证明在实验电极下调节皮层区域的神经连接。虽然在M1区和小脑半球的伽马tACS已被证明可以改善运动表现，但最佳刺激方法尚未明确。在这项研究中，我们旨在阐明γ - tACS对M1和小脑半球的影响是否取决于电流强度。20名健康成人在左M1和右小脑半球的tACS（70 Hz）期间，使用右手食指进行30 s的视觉运动控制任务。每个受试者参加10次试验，间隔时间为3 min。采用三种刺激条件：(1)伪刺激（sham condition），(2)电流强度为1.0 mA的tACS，(3)电流强度为2.0 mA的tACS。我们的研究结果表明，无论电流强度如何，运动表现较低的参与者在两种tACS条件下的运动表现都更好。在假手术条件下没有观察到这种相关性。总的来说，我们的研究结果表明，伽马tACS对M1和小脑半球的影响不依赖于电流强度，运动表现较差的参与者在两种tACS条件下的运动表现略有改善。
Transcranial alternating current stimulation (tACS) has been shown to modulate neural connectivity in the cortical area under experimental electrodes. Although gamma tACS over the M1 region and the cerebellar hemisphere has been shown to improve motor performance, the optimal stimulation method has not been clarified. In this study, we aimed to clarify whether the effect of gamma tACS over M1 and the cerebellar hemisphere depends on current intensity. Twenty healthy adults performed a visuomotor control task using their right index finger for 30 s during tACS (70 Hz) over the left M1 and the right cerebellar hemisphere. Each subject participated in 10 trials, separated by intervals of 3 min. Three stimulation conditions were applied: (1) pseudo-stimulation (sham condition), (2) tACS with a current intensity of 1.0 mA and (3) tACS with a current intensity of 2.0 mA. Our results indicated that regardless of the current intensity, participants with the lower motor performance had better motor performance under both tACS conditions. Such a correlation was not observed under the sham condition. Collectively, our findings demonstrated that the effect of gamma tACS over M1 and the cerebellar hemisphere does not depend on current intensity, and that motor performance slightly improved in both tACS conditions for participants with lower motor performance.
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影响因子：
3.1
作者：
Antal A;Herrmann CS
通讯作者：
Herrmann CS
影响因子：
3.1
作者：
Naro, Antonino;Bramanti, Alessia;Calabro, Rocco Salvatore
通讯作者：
Calabro, Rocco Salvatore
影响因子：
7.7
作者：
Raco, Valerio;Bauer, Robert;Gharabaghi, Alireza
通讯作者：
Gharabaghi, Alireza
影响因子：
4.8
作者：
Mary, Alison;Wens, Vincent;Peigneux, Philippe
通讯作者：
Peigneux, Philippe
影响因子：
9.2
作者：
Helfrich, Randolph F.;Schneider, Till R.;Herrmann, Christoph S.
通讯作者：
Herrmann, Christoph S.