Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis.
Coffee Consumption and Risk of Hypertension in Adults: Systematic Review and Meta-Analysis.
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DOI：
10.3390/nu15133060
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发表时间：
2023-07-07
期刊：
影响因子：
5.9
通讯作者：
Silveira, Erika Aparecida
中科院分区：
文献类型：
--
作者：
Haghighatdoost, Fahimeh;Hajihashemi, Parisa;de Sousa Romeiro, Amanda Maria;Mohammadifard, Noushin;Sarrafzadegan, Nizal;de Oliveira, Cesar;Silveira, Erika Aparecida
目的：咖啡摄入量与高血压(HTN)风险之间的关联存在争议。因此，这项系统性综述和荟萃分析旨在总结当前观察性研究中咖啡与高血压风险之间的联系的证据。方法：应用计算机检索PubMed/Medline和Web of Science，检索截至2023年2月的观察性研究。目前的荟萃分析(注册编号：CRD42022371494)包括了观察性研究，这些研究评估了最高咖啡消费量类别与最低咖啡摄入量类别的HTN风险。用随机效应模型评价了咖啡对HTN的混合效应。结果：25项研究，即13项横断面研究和12个队列被确定为合格。结合从队列研究中提取的13种效应大小显示，较高的咖啡消费量与HTN风险降低7%相关(95%CI：0.88，0.97；I2：22.3%)，而结合来自横断面研究的16种效应大小显示HTN风险的更大降低(RR=0.79，95%CI：0.72，0.87；I2=63.2%)。这些结果因研究特点而异，如研究区域、参与者性别、研究质量和样本量。结论：在横断面研究和队列研究中，咖啡摄入量与高血压风险之间存在负相关。然而，这种联系依赖于研究的特点。考虑到这些因素，还需要进一步的研究来证实本研究的结果。
Objectives: The association between coffee intake and hypertension (HTN) risk is controversial. Therefore, this systematic review and meta-analysis aimed at summarizing the current evidence on the association of coffee with hypertension risk in observational studies. Methods: PubMed/Medline and Web of Science were searched for observational studies up to February 2023. Observational studies which assessed the risk of HTN in the highest category of coffee consumption in comparison with the lowest intake were included in the current meta-analysis (registration number: CRD42022371494). The pooled effect of coffee on HTN was evaluated using a random-effects model. Results: Twenty-five studies i.e., thirteen cross-sectional studies and twelve cohorts were identified to be eligible. Combining 13 extracted effect sizes from cohort studies showed that higher coffee consumption was associated with 7% reduction in the risk of HTN (95% CI: 0.88, 0.97; I2: 22.3%), whereas combining 16 effect sizes from cross-sectional studies illustrated a greater reduction in HTN risk (RR = 0.79, 95% CI: 0.72, 0.87; I2 = 63.2%). These results varied by studies characteristics, such as the region of study, participants’ sex, study quality, and sample size. Conclusions: An inverse association was found between coffee consumption and hypertension risk in both cross-sectional and cohort studies. However, this association was dependent on studies characteristics. Further studies considering such factors are required to confirm the results of this study.
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影响因子：
--
作者：
Klag, MJ;Wang, NY;Ford, DE
通讯作者：
Ford, DE
影响因子：
4.5
作者：
通讯作者：
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DOI：
10.3390/antiox11020379
发表时间：
2022-02-14
期刊：
Antioxidants (Basel, Switzerland)
影响因子：
--
作者：
Barré T;Fontaine H;Pol S;Ramier C;Di Beo V;Protopopescu C;Marcellin F;Bureau M;Bourlière M;Dorival C;Petrov-Sanchez V;Asselah T;Delarocque-Astagneau E;Larrey D;Duclos-Vallée JC;Carrat F;Carrieri P;On Behalf Of The Anrs/Afef Hepather Study Group
通讯作者：
On Behalf Of The Anrs/Afef Hepather Study Group
影响因子：
5
作者：
Chei, Choy-Lye;Loh, Julian Kenrick;Koh, Woon-Puay
通讯作者：
Koh, Woon-Puay
影响因子：
9.3
作者：
Chieng, David;Kistler, Peter M.
通讯作者：
Kistler, Peter M.