Stem cells in the face: tooth regeneration and beyond.
Stem cells in the face: tooth regeneration and beyond.
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DOI:
10.1016/j.stem.2012.08.010
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发表时间:
2012-09-07
期刊:
影响因子:
23.9
通讯作者:
Prockop, Darwin J.
中科院分区:
文献类型:
--
作者:
Mao, Jeremy J.;Robey, Pamela G.;Prockop, Darwin J.
Postnatal orofacial tissues contain rare cells that exhibit stem/progenitor cell properties. Despite a tremendous unmet clinical need for regeneration of tissues lost in congenital anomalies, infections, trauma or tumor resection, how orofacial stem/progenitor cells contribute to tissue development, pathogenesis and regeneration is largely a mystery. This perspective article critically analyzes the current status of orofacial stem/progenitor cells, identifies gaps in our understanding and highlights pathways for the development of regenerative therapies.
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