The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review.
The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review.
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DOI：
10.1007/s00705-002-0888-1
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发表时间：
2002-11
影响因子：
2.7
通讯作者：
Wang C
中科院分区：
文献类型：
--
作者：
Miguel B;Pharr GT;Wang C
猫氨肽酶N（fAPN）已被证明是猫、犬、猪和人冠状病毒的受体。我们的目的是确定fAPN是否可以作为传染性支气管炎病毒（IBV）的受体。将表达fAPN的猫肾细胞和不表达fAPN的仓鼠肾成纤维细胞接种IBV，并通过间接荧光测定和共聚焦显微镜和鸡胚蛋中监测复制。结果表明，猫细胞对IBV具有免疫反应性，而仓鼠细胞对IBV无免疫反应。仓鼠细胞在转染fAPN cDNA后变得允许IBV，表明猫APN分子在IBV进入中起作用。
Feline aminopeptidase N (fAPN) has been shown to serve as a receptor for feline, canine, porcine and human coronaviruses. Our objective was to determine if fAPN can serve as a receptor for infectious bronchitis virus (IBV). Feline kidney cells that express fAPN and hamster kidney fibroblasts that do not express fAPN were inoculated with IBV and monitored for replication by indirect fluorescent assay and confocal microscopy and in chicken embryonated eggs. The results showed that the feline cells were permissive to IBV but the hamster cells were not. The hamster cells became permissive to IBV after transfection with a fAPN cDNA suggesting that the feline APN molecule plays a role in IBV entry.
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影响因子：
1.6
作者：
KWON, HM;JACKWOOD, MW
通讯作者：
JACKWOOD, MW
影响因子：
3.8
作者：
KOCH, G;HARTOG, L;VANROOZELAAR, DJ
通讯作者：
VANROOZELAAR, DJ
影响因子：
4.4
作者：
Gal-Garber, O;Uni, Z
通讯作者：
Uni, Z
氨基肽酶N是肠道病毒冠状病毒TGEV的主要受体。
影响因子：
64.8
作者：
Delmas B;Gelfi J;L'Haridon R;Vogel LK;Sjöström H;Norén O;Laude H
通讯作者：
Laude H
影响因子：
5.4
作者：
Benbacer, L;Kut, E;Delmas, B
通讯作者：
Delmas, B