Towards conceptualizing a neural systems-based anatomy of attention-deficit/hyperactivity disorder.
Towards conceptualizing a neural systems-based anatomy of attention-deficit/hyperactivity disorder.
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DOI:
10.1159/000207492
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发表时间:
2009
影响因子:
2.9
通讯作者:
Seidman LJ
中科院分区:
文献类型:
--
作者:
Makris N;Biederman J;Monuteaux MC;Seidman LJ
Convergent data from neuroimaging, neuropsychological, genetic and neurochemical studies in attention-deficit/hyperactivity disorder (ADHD) have implicated dysfunction of the dorsolateral prefrontal cortex (DLPFC) and dorsal anterior cingulate cortex (dACC), which form the cortical arm of the frontostriatal network supporting executive functions. Furthermore, besides the DLPFC and dACC, structural and functional imaging studies have shown abnormalities in key brain regions within distributed cortical networks supporting attention. The conceptualization of neural systems biology in ADHD aims at the understanding of what organizing principles have been altered during development within the brain of a person with ADHD. Characterizing these neural systems using neuroimaging could be critical for the description of structural endophenotypes, and may provide the capability of in vivo categorization and correlation with behavior and genes.
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影响因子:
9.9
作者:
Baumgardner, TL;Singer, HS;Reiss, AL
通讯作者:
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影响因子:
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作者:
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DOI:
10.3109/15622970209150624
发表时间:
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期刊:
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
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作者:
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通讯作者:
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