Effects of shampoo and water washing on hair cortisol concentrations.
Effects of shampoo and water washing on hair cortisol concentrations.
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DOI：
10.1016/j.cca.2010.10.019
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发表时间：
2011-01-30
期刊：
影响因子：
--
通讯作者：
Novak MA
中科院分区：
文献类型：
--
作者：
Hamel AF;Meyer JS;Henchey E;Dettmer AM;Suomi SJ;Novak MA
头发中皮质醇的测量是人类和非人类灵长类动物慢性压力的新兴生物标志物。然而，目前尚不清楚反复接触洗发水和/或水的头发潜在皮质醇损失的程度。来自 20 只恒河猴的混合毛发样本接受了五种处理条件：10、20 或 30 次洗发水洗涤、20 次仅用水洗涤或不洗涤对照。每次洗涤时，将头发暴露在稀释的洗发水溶液或自来水中45秒，用自来水冲洗4次，然后快速干燥。然后使用先前公布的方法对样品进行皮质醇提取和分析。洗发后头发皮质醇水平显着降低，洗发水次数与皮质醇浓度呈反比关系。这种影响主要是由于接触水造成的，因为 20 次纯水洗涤后的皮质醇水平与 20 次洗发水处理后的皮质醇水平相似。无论是否使用洗发水，反复接触水似乎都会从头发中滤出皮质醇，产生的值低估了发干内慢性激素沉积的量。在进行人类头发皮质醇研究时，收集头皮附近的样本并获得洗发频率数据可能很有价值。
Measurement of cortisol in hair is an emerging biomarker for chronic stress in human and nonhuman primates. Currently unknown, however, is the extent of potential cortisol loss from hair that has been repeatedly exposed to shampoo and/or water. Pooled hair samples from 20 rhesus monkeys were subjected to five treatment conditions: 10, 20, or 30 shampoo washes, 20 water-only washes, or a no-wash control. For each wash, hair was exposed to a dilute shampoo solution or tap water for 45 s, rinsed 4 times with tap water, and rapidly dried. Samples were then processed for cortisol extraction and analysis using previously published methods. Hair cortisol levels were significantly reduced by washing, with an inverse relationship between number of shampoo washes and the cortisol concentration. This effect was mainly due to water exposure, as cortisol levels following 20 water-only washes were similar to those following 20 shampoo treatments. Repeated exposure to water with or without shampoo appears to leach cortisol from hair, yielding values that underestimate the amount of chronic hormone deposition within the shaft. Collecting samples proximal to the scalp and obtaining hair washing frequency data may be valuable when conducting human hair cortisol studies.
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影响因子：
2.2
作者：
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通讯作者：
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DOI：
10.1080/10253890801887388
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