Densonucleosis viruses ('densoviruses') for mosquito and pathogen control.
Densonucleosis viruses ('densoviruses') for mosquito and pathogen control.
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DOI:
10.1016/j.cois.2018.05.009
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发表时间:
2018-08
影响因子:
5.3
通讯作者:
Rasgon JL
中科院分区:
文献类型:
--
作者:
Johnson RM;Rasgon JL
Mosquito specific viruses such as densonucleosis viruses (“densoviruses”) have long been suggested as alternative mosquito control agents in the face of increasing insecticide resistance. Densoviruses are very species-specific and have been found to infect many important mosquito species. While some strains are highly pathogenic, other strains are more benign. Densoviruses have been proposed as a way to reduce mosquito populations through pathogenic interactions, but genetic strategies such as viral paratrangenesis offer new approaches. As small single-stranded DNA viruses, densoviruses can be easily genetically modified for the expression of genes or non-coding RNAs. A growing literature and variety of techniques have shown the potential for the use of densoviruses in the control of mosquitoes or mosquito-borne pathogens as well as the usefulness of densoviruses as molecular tools for understanding mosquito biology.
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