Preparation of Mineralized Electrospun PCL/Gelatin Scaffolds via Double Diffusion System
Preparation of Mineralized Electrospun PCL/Gelatin Scaffolds via Double Diffusion System
复制标题
双扩散系统制备矿化电纺 PCL/明胶支架
DOI：
10.4028/www.scientific.net/kem.512-515.1740
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发表时间：
2012-06
期刊：
影响因子：
--
通讯作者：
周长忍
中科院分区：
文献类型：
--
作者：
郭振招;李红;关伟成;薛博;周长忍
为了成功重建骨骼缺损，一系列包括陶瓷、聚合物及其复合材料在内的材料已经被研发出来。我们工作的目标是在一种双扩散系统中制备矿化的聚己内酯/明胶复合支架，因为……（句子不完整）
For successful reconstruction of skeletal defects, a range of materials including ceramics, polymers and their composites have been developed. The goal of our work is to prepare mineralized PCL/gelatin composite scaffolds in a double diffusion system as implants for bone tissue engineering application. Fibrous PCL/gelatin scaffold fabricated via electrospinning followed by immersing into disodium-β-glycerophosphate(β-GP) (10 mg/ml) for 12h were used as substrates for calcium phosphate (CaP) mineralization. The precipitation reaction was biomimetically carried out in a double diffusion system for a week. The CaP minerals precipitated on the scaffold were characterized by X-ray powder diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy and high-resolution transmission electron microscopy. The results show that apatite aggregates are combination of HAP, DCPD and ACP. β-GP can effectively promote the formation of CaP crystals. The composite scaffold fabricated in this paper hold promise for use in bone tissue engineering.
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影响因子：
--
作者：
Falini, G;Gazzano, M;Ripamonti, A
通讯作者：
Ripamonti, A
DOI：
10.1007/s10856-010-4048-y
发表时间：
2010-06-01
影响因子：
3.7
作者：
Nguyen Thi Hiep;Lee, Byong-Taek
通讯作者：
Lee, Byong-Taek
用于骨组织工程的仿生纳米纤维明胶/磷灰石复合支架。
影响因子：
14
作者：
Liu, Xiaohua;Smith, Laura A.;Hu, Jiang;Ma, Peter X.
通讯作者：
Ma, Peter X.
影响因子：
4.9
作者：
Del Gaudio, Costantino;Bianco, Alessandra;Grigioni, Mauro
通讯作者：
Grigioni, Mauro
影响因子：
9.7
作者：
Chong, E. J.;Phan, T. T.;Lim, C. T.
通讯作者：
Lim, C. T.