Effect of Intraocular Forward Scattering and Corneal Higher-Order Aberrations on Visual Acuity after Descemet's Stripping Automated Endothelial Keratoplasty.
Effect of Intraocular Forward Scattering and Corneal Higher-Order Aberrations on Visual Acuity after Descemet's Stripping Automated Endothelial Keratoplasty.
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DOI：
10.1371/journal.pone.0131110
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Igarashi A
中科院分区：
文献类型：
--
作者：
Kamiya K;Asato H;Shimizu K;Kobashi H;Igarashi A
评估后弹力层剥脱式自动内皮角膜移植术（DSAEK）后眼内前向散射和角膜高阶像差（HOA）与最佳眼镜矫正视力（BSCVA）的关系，并比较DSAEK组和非后弹力层剥脱式自动内皮角膜移植术（n-DSAEK）组的这些参数。这项回顾性研究纳入了30例连续患者的30只眼，这些患者接受了标准DSAEK，并在DSAEK之前成功接受了超声乳化联合人工透镜植入术。手术时的平均年龄为71.7 ± 10.4岁。术后3个月，我们使用双通仪器（OQAS II，Visiometrics）定量评估了客观散射指数（OSI），并使用Hartmann-Shack像差仪（KR-9000PW，Topcon）定量评估了角膜HOA。DSAEK后3个月的平均OSI、角膜HOA和logMAR BSCVA分别为7.91 ± 3.58、0.43 ± 0.27 μ m和0.32 ± 0.25。我们发现OSI与logMAR BSCVA之间存在显著相关性（斯皮尔曼相关系数r = 0.714，p <0.001），但术后3个月角膜HOA与logMAR BSCVA之间无显著相关性（r = 0.209，p = 0.267）。我们发现DSAEK和n-DSAEK组之间的任何术后参数均无显著差异（p> 0.05）。我们的初步研究表明，术后矫正视力与眼内前向散射显著相关，但与DSAEK术后眼的角膜HOA无关，这表明眼内前向散射在DSAEK术后的视觉表现中比角膜像差起着更重要的作用。详细的视觉性能，如HOA和眼内散射，n-DSAEK后似乎基本上等同于DSAEK后。
To assess the relationship of intraocular forward scattering and corneal higher-order aberrations (HOAs) with best spectacle corrected visual acuity (BSCVA) after Descemet’s stripping automated endothelial keratoplasty (DSAEK), and to compare these parameters between DSAEK and non-Descemet’s stripping automated endothelial keratoplasty (n-DSAEK) groups. This retrospective study enrolled thirty eyes of 30 consecutive patients who underwent standard DSAEK, and who underwent successful phacoemulsification with intraocular lens implantation before DSAEK. The mean age at the time of surgery was 71.7 ± 10.4 years. We quantitatively evaluated the objective scattering index (OSI) using the double-pass instrument (OQAS II, Visiometrics) and corneal HOAs using Hartmann-Shack aberrometry (KR-9000PW, Topcon) 3 months postoperatively. The mean OSI, corneal HOAs, and logMAR BSCVA 3 months after DSAEK were 7.91 ± 3.58, 0.43 ± 0.27 μm, and 0.32 ± 0.25, respectively. We found a significant correlation between the OSI and logMAR BSCVA (Spearman correlation coefficient r=0.714, p<0.001), but no significant association between corneal HOAs and logMAR BSCVA 3 months postoperatively (r=0.209, p=0.267). We found no significant differences in any postoperative parameters between the DSAEK and n-DSAEK groups (p>0.05). Our pilot study demonstrated that the postoperative corrected visual acuity was significantly correlated with intraocular forward scattering, but not with corneal HOAs in post-DSAEK eyes, suggesting that intraocular forward scattering plays a more essential role in postoperative visual performance than corneal aberrations after DSAEK. The detailed visual performance, such as HOAs and intraocular scattering, after n-DSAEK appears to be essentially equivalent to that after DSAEK.
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