In Vivo Application of Silica-Derived Inks for Bone Tissue Engineering: A 10-Year Systematic Review.
In Vivo Application of Silica-Derived Inks for Bone Tissue Engineering: A 10-Year Systematic Review.
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DOI：
10.3390/bioengineering9080388
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发表时间：
2022-08-15
期刊：
影响因子：
--
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中科院分区：
文献类型：
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由于需要高效，可持续，可定制，方便和负担得起的替代材料用于骨修复是至关重要的，本系统综述旨在评估二氧化硅衍生油墨的使用和结果，以促进体内骨再生。按照PRISMA指南和皮科方法进行文献算法选择。经初步筛选，共纳入51篇文献。油墨配方中的硅大多数被发现存在于天然材料中，但与次要角色相关，或者是用于掺杂现有材料的关键添加剂元素。本文介绍的油墨和材料基本上是基于挤出的3D打印（80%），总体而言，研究最多的动物模型是具有股骨缺损（51%）的兔子（65%）。质量（ARRIVE 2.0）和偏倚风险（SYRCLE）评估概述，尽管大多数ARRIVE项目已“报告”，但由于缺乏准确信息，大多数偏倚风险仍“不清楚”。几乎所有的研究，尽管有广泛的策略和配方，报告他们的二氧化硅衍生材料，以改善骨再生。在过去的几年里，越来越多的出版物强调了硅作为骨组织工程的杠杆因素，在未来密切考虑。
As the need for efficient, sustainable, customizable, handy and affordable substitute materials for bone repair is critical, this systematic review aimed to assess the use and outcomes of silica-derived inks to promote in vivo bone regeneration. An algorithmic selection of articles was performed following the PRISMA guidelines and PICO method. After the initial selection, 51 articles were included. Silicon in ink formulations was mostly found to be in either the native material, but associated with a secondary role, or to be a crucial additive element used to dope an existing material. The inks and materials presented here were essentially extrusion-based 3D-printed (80%), and, overall, the most investigated animal model was the rabbit (65%) with a femoral defect (51%). Quality (ARRIVE 2.0) and risk of bias (SYRCLE) assessments outlined that although a large majority of ARRIVE items were “reported”, most risks of bias were left “unclear” due to a lack of precise information. Almost all studies, despite a broad range of strategies and formulations, reported their silica-derived material to improve bone regeneration. The rising number of publications over the past few years highlights Si as a leverage element for bone tissue engineering to closely consider in the future.
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影响因子：
7.5
作者：
Gibon E;Lu L;Goodman SB
通讯作者：
Goodman SB
影响因子：
--
作者：
Boularaoui, Selwa;Al Hussein, Ghada;Stefanini, Cesare
通讯作者：
Stefanini, Cesare
影响因子：
3.2
作者：
Berg, J. Michael;Romoser, Amelia A.;Sayes, Christie M.
通讯作者：
Sayes, Christie M.
影响因子：
12.4
作者：
Deng C;Zhu H;Li J;Feng C;Yao Q;Wang L;Chang J;Wu C
通讯作者：
Wu C
DOI：
10.3390/ph14020075
发表时间：
2021-01-20
期刊：
Pharmaceuticals (Basel, Switzerland)
影响因子：
--
作者：
Al-Harbi N;Mohammed H;Al-Hadeethi Y;Bakry AS;Umar A;Hussein MA;Abbassy MA;Vaidya KG;Berakdar GA;Mkawi EM;Nune M
通讯作者：
Nune M