Current situation of H9N2 subtype avian influenza in China.

Current situation of H9N2 subtype avian influenza in China.
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我国H9N2亚型禽流感现状

DOI:
10.1186/s13567-017-0453-2
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发表时间:
2017-09-15
影响因子:
4.4
通讯作者:
Liu X
Liu X
中科院分区:
农林科学2区
文献类型:
--
作者:
Gu M;Xu L;Wang X;Liu X

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在中国,H9N2亚型禽流感于1992年首次在广东省暴发。随后,该病蔓延到全国绝大多数地区,目前已成为当地的地方病。经过多年的遗传进化,病毒的致病性和传播力呈逐年上升的趋势,对家禽业构成严重威胁。此外,H9N2不仅可以直接感染人类,还可以捐赠部分甚至整个内部基因盒,产生H5N1, H7N9, H10N8和H5N6病毒等新的人类致命重组病毒,对公共卫生具有重要意义。本文主要从H9N2亚型禽流感病毒在中国的流行病学动态、生物学特征、分子系统发育和疫苗策略等方面综述了中国H9N2亚型禽流感病毒的流行病学动态、生物学特征、分子系统发育和疫苗策略。
In China, H9N2 subtype avian influenza outbreak is firstly reported in Guangdong province in 1992. Subsequently, the disease spreads into vast majority regions nationwide and has currently become endemic there. Over vicennial genetic evolution, the viral pathogenicity and transmissibility have showed an increasing trend as year goes by, posing serious threat to poultry industry. In addition, H9N2 has demonstrated significance to public health as it could not only directly infect mankind, but also donate partial or even whole cassette of internal genes to generate novel human-lethal reassortants like H5N1, H7N9, H10N8 and H5N6 viruses. In this review, we mainly focused on the epidemiological dynamics, biological characteristics, molecular phylogeny and vaccine strategy of H9N2 subtype avian influenza virus in China to present an overview of the situation of H9N2 in China.
DOI: 10.1128/jvi.74.20.9372-9380.2000
发表时间: 2000-10-01
影响因子: 5.4
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