Resting cerebral metabolism correlates with skin conductance and functional brain activation during fear conditioning.
Resting cerebral metabolism correlates with skin conductance and functional brain activation during fear conditioning.
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DOI：
10.1016/j.biopsycho.2011.12.012
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发表时间：
2012-02
影响因子：
2.6
通讯作者：
Milad, Mohammed R.
中科院分区：
文献类型：
--
作者：
Linnman, Clas;Zeidan, Mohamed A.;Pitman, Roger K.;Milad, Mohammed R.
我们调查了20名健康人的静息脑代谢是否可以用来预测恐惧条件反射过程中的自主神经和神经元反应。静息状态下通过正电子发射断层扫描测量局部脑葡萄糖代谢率。在条件反射过程中，通过皮肤电导测量自主神经反应，通过功能性磁共振成像测量血氧水平依赖性信号。静息背侧前扣带代谢阳性预测差异条件皮肤电导反应。中脑和背侧扣带回静息代谢负预测中脑和背侧扣带回功能反应性，而背侧前扣带回静息代谢正预测中脑功能反应性。我们的结论是，在边缘区的静息代谢可以预测恐惧学习过程中的心理生理和神经元反应的某些方面。
We investigated whether resting brain metabolism can be used to predict autonomic and neuronal responses during fear conditioning in 20 healthy humans. Regional cerebral metabolic rate for glucose was measured via positron emission tomography at rest. During conditioning, autonomic responses were measured via skin conductance, and blood oxygen level dependent signal was measured via functional magnetic resonance imaging. Resting dorsal anterior cingulate metabolism positively predicted differentially conditioned skin conductance responses. Midbrain and insula resting metabolism negatively predicted midbrain and insula functional reactivity, while dorsal anterior cingulate resting metabolism positively predicted midbrain functional reactivity. We conclude that resting metabolism in limbic areas can predict some aspects of psychophysiological and neuronal reactivity during fear learning.
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DOI：
10.1523/jneurosci.2021-06.2006
发表时间：
2006-09-13
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Kalisch R;Korenfeld E;Stephan KE;Weiskopf N;Seymour B;Dolan RJ
通讯作者：
Dolan RJ
影响因子：
5.7
作者：
Linnman, Clas;Moulton, Eric A.;Barmettler, Gabi;Becerra, Lino;Borsook, David
通讯作者：
Borsook, David
影响因子：
2
作者：
Cheng, Dominic T.;Richards, Jennifer;Helmstetter, Fred J.
通讯作者：
Helmstetter, Fred J.
影响因子：
5.7
作者：
Maldjian, JA;Laurienti, PJ;Burdette, JH
通讯作者：
Burdette, JH
影响因子：
82.9
作者：
Judenhofer, Martin S.;Wehrl, Hans F.;Pichler, Bernd J.
通讯作者：
Pichler, Bernd J.