Behavioral inhibition and risk for developing social anxiety disorder: a meta-analytic study.
Behavioral inhibition and risk for developing social anxiety disorder: a meta-analytic study.
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DOI：
10.1016/j.jaac.2012.08.002
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发表时间：
2012-10
影响因子：
13.3
通讯作者：
Blackford JU
中科院分区：
文献类型：
--
作者：
Clauss JA;Blackford JU
行为抑制（BI）与社交焦虑障碍（SAD）的风险增加有关;然而，与BI相关的风险程度尚未得到系统的检查和量化。本研究的目的是量化儿童BI和SAD风险之间的关系。进行了全面的文献检索，以识别评估BI和SAD的研究。进行荟萃分析，以估计儿童BI和SAD之间相关性的比值比（OR）。7项研究符合纳入标准。BI与发生SAD的风险增加7倍以上相关（比值比= 7.59，p <0.00002）。即使在考虑了气质评估、对照组、父母风险、气质评估时的年龄和焦虑诊断时的年龄的研究差异后，这种关联仍然显着。识别早期发育风险因素对于预防精神疾病至关重要。考虑到15%的儿童表现出极端的BI，并且这些受抑制的儿童中几乎有一半最终会发展为SAD，我们认为BI是发展SAD的最大单一风险因素之一。
Behavioral inhibition (BI) has been associated with increased risk for developing social anxiety disorder (SAD); however, the degree of risk associated with BI has yet to be systematically examined and quantified. The goal of the present study was to quantify the association between childhood BI and risk for developing SAD. A comprehensive literature search was conducted to identify studies that assessed both BI and SAD. Meta-analyses were performed to estimate the odds ratio (OR) of the association between BI and SAD in children. Seven studies met inclusion criteria. BI was associated with a greater than sevenfold increase in risk for developing SAD (odds ratio = 7.59, p < .00002). This association remained significant even after considering study differences in temperament assessment, control group, parental risk, age at temperament assessment, and age at anxiety diagnosis. Identifying early developmental risk factors is critical for preventing psychiatric illness. Given that 15% of all children show extreme BI, and that almost half of these inhibited children will eventually develop SAD, we propose that BI is one of the largest single risk factors for developing SAD.
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影响因子：
--
作者：
Guyer, Amanda E.;Lau, Jennifer Y. F.;McClure-Tone, Erin B.;Parrish, Jessica;Shiffrin, Nina D.;Reynolds, Richard C.;Chen, Gang;Blair, R. J. R.;Leibenluft, Ellen;Fox, Nathan A.;Ernst, Monique;Pine, Daniel S.;Nelson, Eric E.
通讯作者：
Nelson, Eric E.
DOI：
10.1097/chi.0b013e3181ae09df
发表时间：
2009-09
影响因子：
13.3
作者：
Chronis-Tuscano A;Degnan KA;Pine DS;Perez-Edgar K;Henderson HA;Diaz Y;Raggi VL;Fox NA
通讯作者：
Fox NA
影响因子：
4.2
作者：
Blackford, Jennifer Urbano;Avery, Suzanne N.;Zald, David H.
通讯作者：
Zald, David H.
影响因子：
10.6
作者：
Kagan, J;Snidman, N
通讯作者：
Snidman, N
影响因子：
4.6
作者：
KAGAN, J;REZNICK, JS;JOHNSON, MO
通讯作者：
JOHNSON, MO