Imaging the rapidly developing brain: Current challenges for MRI studies in the first five years of life.
Imaging the rapidly developing brain: Current challenges for MRI studies in the first five years of life.
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快速发育的大脑成像:生命前五年MRI研究的当前挑战
DOI:
10.1016/j.dcn.2020.100893
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发表时间:
2021-03
影响因子:
4.7
通讯作者:
Gaab N
中科院分区:
文献类型:
--
作者:
Turesky TK;Vanderauwera J;Gaab N
Rapid and widespread changes in brain anatomy and physiology in the first five years of life present substantial challenges for developmental structural, functional, and diffusion MRI studies. One persistent challenge is that methods best suited to earlier developmental stages are suboptimal for later stages, which engenders a trade-off between using different, but age-appropriate, methods for different developmental stages or identical methods across stages. Both options have potential benefits, but also biases, as pipelines for each developmental stage can be matched on methods or the age-appropriateness of methods, but not both. This review describes the data acquisition, processing, and analysis challenges that introduce these potential biases and attempts to elucidate decisions and make recommendations that would optimize developmental comparisons.
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