Mechanical characterization of proanthocyanidin-dentin matrix interaction.
Mechanical characterization of proanthocyanidin-dentin matrix interaction.
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DOI：
10.1016/j.dental.2010.06.001
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发表时间：
2010-10
期刊：
影响因子：
--
通讯作者：
Bedran-Russo AK
中科院分区：
文献类型：
--
作者：
Castellan CS;Pereira PN;Grande RH;Bedran-Russo AK
研究两种富含原花青素的交联剂处理牙本质基质的性质及其对牙本质结合界面的影响。将健康的人磨牙切成0.5 mm厚的牙本质板，脱矿，并用两种交联剂（葡萄籽- GSE和可可籽- COE提取物）中的一种处理或不处理。分别于处理10 min和60 min后测定脱矿牙本质的弹性模量，并于处理60 min后测定其膨胀率。细菌胶原酶也用于评估经受极限拉伸强度的样品对酶降解的抗性。在暴露10或60 min后评价GSE或COE对树脂-牙本质粘结强度的影响。在95%置信区间对数据进行统计分析。随着暴露时间的增加，两种交联剂都增加了脱矿牙本质的弹性模量。与对照组相比，处理样品的溶胀率较低。UTS无统计学显著变化表明胶原酶对GSE或COE处理的牙本质基质无影响。牙本质树脂债券显着增加治疗后与GSE无论应用时间或粘合剂系统使用。通过使用富含PA的胶原交联剂可以提高牙本质基质的机械性能和稳定性，这很可能是由于PA-胶原复合物的形成。牙本质处理10分钟后，牙本质-树脂的短期粘结可得到改善。
To characterize the properties of dentin matrix treated with two proanthocyanidin rich cross-linking agents and their effect on dentin bonded interfaces. Sound human molars were cut into 0.5 mm thick dentin slabs, demineralized and either treated with one of two cross-linking agents (grape seed - GSE and cocoa seed - COE extracts) or left untreated. The modulus of elasticity of demineralized dentin was assessed after 10 or 60 min and the swelling ratio after 60 min treatment. Bacterial collagenase was also used to assess resistance to enzymatic degradation of samples subjected to ultimate tensile strength. The effect of GSE or COE on the resin-dentin bond strength was evaluated after 10 or 60 min of exposure time. Data were statistically analyzed at a 95% confidence interval. Both cross-linkers increased the elastic modulus of demineralized dentin as exposure time increased. Swelling ratio was lower for treated samples when compared to control groups. No statistically significant changes to the UTS indicate that collagenase had no effect on dentin matrix treated with either GSE or COE. Dentin-resin bonds significantly increased following treatment with GSE regardless of the application time or adhesive system used. Increased mechanical properties and stability of dentin matrix can be achieved by the use of PA-rich collagen cross-linkers most likely due to the formation of a PA-collagen complex. The short term dentin-resin bonds can be improved after 10 minutes dentin treatment.
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影响因子：
4.1
作者：
RIGAUD, J;ESCRIBANOBAILON, MT;CHEYNIER, V
通讯作者：
CHEYNIER, V
影响因子：
14
作者：
Pek, YS;Spector, M;Gibson, LJ
通讯作者：
Gibson, LJ
影响因子：
4.1
作者：
Núñez, V;Gómez-Cordovés, C;Mitchell, AE
通讯作者：
Mitchell, AE
DOI：
10.1002/jmb.b.31022
发表时间：
2008-08-01
影响因子：
3.4
作者：
Bedran-Russo, Ana Karina B.;Pashley, David H.;Miescke, Klaus J.
通讯作者：
Miescke, Klaus J.
影响因子：
14
作者：
Charulatha, V;Rajaram, A
通讯作者：
Rajaram, A