A hybrid PDMS-Parylene subdural multi-electrode array.

A hybrid PDMS-Parylene subdural multi-electrode array.
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DOI:
10.1007/s10544-013-9743-2
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发表时间:
2013-06
影响因子:
2.8
通讯作者:
Ziaie, Babak
Ziaie, Babak
中科院分区:
工程技术3区
文献类型:
--
作者:
Ochoa, Manuel;Wei, Pinghung;Wolley, Andrew J.;Otto, Kevin J.;Ziaie, Babak

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在本文中,我们报告了一种成本有效且简单的方法来制造用于硬膜下神经记录的柔性多电极阵列。该电极采用 PDMS-聚对二甲苯双层制造,结合了两种材料的主要优点。进行机械和电气表征以确认 16 点电极阵列在各种弯曲/弯曲条件下的功能。电极阵列螺旋缠绕在直径 3 毫米的圆柱形管上,并放置在直径 2 厘米的球体上,同时保持其记录能力。实验结果显示,对于 90 μm 直径的金记录位点,1 kHz 时的阻抗值在 300 kΩ 和 600 kΩ 之间。成功记录了大鼠听觉皮层的声诱发神经活动,证实了其体内功能。
In this paper, we report on a cost effective and simple method for fabricating a flexible multi-electrode array for subdural neural recording. The electrode was fabricated using a PDMS-Parylene bilayer to combine the major advantages of both materials. Mechanical and electrical characterizations were performed to confirm functionality of a 16-site electrode array under various flexed/bent conditions. The electrode array was helically wound around a 3 mm diameter cylindrical tube and laid over a 2 cm diameter sphere while maintaining its recording capability. Experimental results showed impedance values between 300 kΩ and 600 kΩ at 1 kHz for 90 μm diameter gold recording sites. Acoustically evoked neural activity was successfully recorded from rat auditory cortex, confirming in vivo functionality.
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发表时间: 2000-04-15
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