Stabilization of submicron calcium oxalate suspension by chondroitin sulfate C may be an efficient protection from stone formation.
Stabilization of submicron calcium oxalate suspension by chondroitin sulfate C may be an efficient protection from stone formation.
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DOI：
10.1155/2013/360142
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发表时间：
2013
影响因子：
3.8
通讯作者：
Ouyang JM
中科院分区：
文献类型：
--
作者：
Li JJ;Xue JF;Ouyang JM
采用X射线衍射仪、纳米颗粒粒度Zeta电位分析仪、紫外分光光度计和扫描电镜研究了硫酸软骨素C（C6S）对平均粒径约为330 nm的亚微米一水草酸钙（COM）和二水草酸钙（COD）微晶的尺寸、聚集、沉降和Zeta电位的影响。然后将结果与微米级晶体的结果进行比较。C_6S抑制了COD向COM的转化，抑制了COM和COD的聚集结晶，降低了它们的沉降速率，从而提高了它们在水溶液中的稳定性。COD微晶的尺寸越小，它们越容易转化为COM。亚微米级COD的稳定性比微米级晶体差。C6S可抑制草酸钙结石的形成。
The influences of chondroitin sulfate C (C6S) on size, aggregation, sedimentation, and Zeta potential of sub-micron calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD) crystallites with mean sizes of about 330 nm were investigated using an X-ray diffractometer, nanoparticle size Zeta potential analyzer, ultraviolet spectrophotometer, and scanning electron microscope, after which the results were compared with those of micron-grade crystals. C6S inhibited the conversion of COD to COM and the aggregation of COM and COD crystallitesis; it also decreased their sedimentation rate, thus increasing their stability in aqueous solution. The smaller the size of the COD crystallites, the easier they can be converted to COM. The stability of sub-micron COD was worse than that of micron-grade crystals. C6S can inhibit the formation of calcium oxalate stones.
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影响因子：
1
作者：
Lulich, Jody P.;Osborne, Carl A.;Nakagawa, Yasushi
通讯作者：
Nakagawa, Yasushi
影响因子：
3.1
作者：
Poon, Ngork Wah;Gohel, Mayur Danny I.
通讯作者：
Gohel, Mayur Danny I.
影响因子：
8
作者：
Peng H;Ouyang JM;Yao XQ;Yang RE
通讯作者：
Yang RE
影响因子：
3.9
作者：
He, Jie-Yu;Deng, Sui-Ping;Ouyang, Jian-Ming
通讯作者：
Ouyang, Jian-Ming
影响因子：
9.9
作者：
Christmas, KG;Gower, LB;El-Shall, H
通讯作者：
El-Shall, H