Cecum microbiome and metabolism characteristics of Silky Fowl and White Leghorn chicken in late laying stages.
Cecum microbiome and metabolism characteristics of Silky Fowl and White Leghorn chicken in late laying stages.
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乌骨鸡和白来亨鸡产蛋后期盲肠微生物组及代谢特征
DOI：
10.3389/fmicb.2022.984654
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发表时间：
2022
影响因子：
5.2
通讯作者：
中科院分区：
文献类型：
--
作者：
盲肠菌群对鸡的生产性能和免疫功能起着关键作用。白色来航鸡（WL）是我国著名的高产蛋鸡品系。相比之下，中国本土鸡品种丝羽乌骨鸡（SF）的产蛋率较低，但免疫性能良好。本研究分析了这些品种的盲肠菌群组成、代谢和肠道组织基因表达以及它们之间的相关性。盲肠微生物中观察到显著差异：拟杆菌属显著富集在WL中，而韦荣氏球菌科和副拟杆菌属显著富集在SF中。碳水化合物的生物合成和代谢途径在WL盲肠中显著上调，这可能为宿主提供更多的能量，导致持续高水平的产卵。SF中较高的拟杆菌属丰度增加了volicitin含量，增强了α-亚麻酸代谢，并与丙酸代谢和碳水化合物代谢产物呈显著负相关。与脂质代谢、免疫和黑素生成相关的基因在SF盲肠中显著上调，调节脂质代谢，并参与免疫反应，而与葡萄糖代谢和胆汁酸代谢相关的基因在WL中以较高水平表达，有利于能量支持。本研究为肠道微生物和代谢途径调节鸡产蛋性能和免疫力提供了机制。
Cecal microflora plays a key role in the production performance and immune function of chickens. White Leghorn (WL) is a well-known commercial layer line chicken with high egg production rate. In contrast, Silky Fowl (SF), a Chinese native chicken variety, has a low egg production rate, but good immune performance. This study analyzed the composition of cecal microbiota, metabolism, and gene expression in intestinal tissue of these varieties and the correlations among them. Significant differences were observed in the cecal microbes: Bacteroides was significantly enriched in WL, whereas Veillonellaceae and Parabacteroides were significantly enriched in SF. Carbohydrate biosynthesis and metabolism pathways were significantly upregulated in WL cecum, which might provide more energy to the host, leading to persistently high levels of egg production. The higher Parabacteroides abundance in SF increased volicitin content, enhanced α-linolenic acid metabolism, and significantly negatively correlated with metabolites of propanoate metabolism and carbohydrate metabolism. Genes related to lipid metabolism, immunity, and melanogenesis were significantly upregulated in the SF cecum, regulating lipid metabolism, and participating in the immune response, while genes related to glucose metabolism and bile acid metabolism were expressed at higher levels in WL, benefiting energy support. This study provided a mechanism for intestinal microorganisms and metabolic pathways to regulate chicken egg-laying performance and immunity.
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影响因子：
4.4
作者：
Han D;Tai Y;Hua G;Yang X;Chen J;Li J;Deng X
通讯作者：
Deng X
卵巢卵泡的转录组分析揭示了与鸡蛋产量增加和减少相关的潜在关键基因
影响因子：
3.7
作者：
Chen X;Sun X;Chimbaka IM;Qin N;Xu X;Liswaniso S;Xu R;Gonzalez JM
通讯作者：
Gonzalez JM
影响因子：
48
作者：
Callahan BJ;McMurdie PJ;Rosen MJ;Han AW;Johnson AJ;Holmes SP
通讯作者：
Holmes SP
影响因子：
5.4
作者：
Grygiel-Górniak B
通讯作者：
Grygiel-Górniak B
DOI：
10.1016/j.metabol.2020.154338
发表时间：
2021-01
期刊：
Metabolism: clinical and experimental
影响因子：
--
作者：
Christofides A;Konstantinidou E;Jani C;Boussiotis VA
通讯作者：
Boussiotis VA