Disposable Voltammetric Immunosensors Integrated with Microfluidic Platforms for Biomedical, Agricultural and Food Analyses: A Review.

Disposable Voltammetric Immunosensors Integrated with Microfluidic Platforms for Biomedical, Agricultural and Food Analyses: A Review.
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一次性伏安免疫传感器与微流体平台集成用于生物医学、农业和食品分析:综述。

DOI:
10.3390/s18124124
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发表时间:
2018-11-24
期刊:
Sensors (Basel, Switzerland)
影响因子:
--
通讯作者:
Angnes L
Angnes L
中科院分区:
其他
文献类型:
--
作者:
Felix FS;Baccaro ALB;Angnes L

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一次性免疫传感器是用于对临床、环境、农业和食品质量管理等不同领域的多种分析物进行定量的分析设备。他们通过抗体和抗原之间的强烈相互作用来检测分析物,从而提供浓度依赖性信号。对于本文强调的伏安免疫传感器,分析测量是由于换能器表面上的电信号的变化而产生的。使用一次性和小型化免疫测定的可能性是伏安分析的一个非常有趣的替代方案,主要是与丝网印刷技术(丝网印刷电极,SPE)和微流体平台相关时。本文的目的是讨论精心挑选的有关基于 SPE 的免疫传感器与疾病、食品、农业和环境分析微流体技术相关的不同示例的文献。还将介绍伏安免疫分析发展的技术方面,例如信号放大、纸基微流体平台的构建以及微流体装置用于即时检测的利用。
Disposable immunosensors are analytical devices used for the quantification of a broad variety of analytes in different areas such as clinical, environmental, agricultural and food quality management. They detect the analytes by means of the strong interactions between antibodies and antigens, which provide concentration-dependent signals. For the herein highlighted voltammetric immunosensors, the analytical measurements are due to changes in the electrical signals on the surface of the transducers. The possibility of using disposable and miniaturized immunoassays is a very interesting alternative for voltammetric analyses, mainly, when associated with screen-printing technologies (screen-printed electrodes, SPEs), and microfluidic platforms. The aim of this paper is to discuss a carefully selected literature about different examples of SPEs-based immunosensors associated with microfluidic technologies for diseases, food, agricultural and environmental analysis. Technological aspects of the development of the voltammetric immunoassays such as the signal amplification, construction of paper-based microfluidic platforms and the utilization of microfluidic devices for point-of-care testing will be presented as well.
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