Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs.
Centrifugal telencephalic afferent connections to the main and accessory olfactory bulbs.
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DOI：
10.3389/fnana.2012.00019
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发表时间：
2012
影响因子：
2.9
通讯作者：
Martinez-Marcos A
中科院分区：
文献类型：
--
作者：
Mohedano-Moriano A;de la Rosa-Prieto C;Saiz-Sanchez D;Ubeda-Bañon I;Pro-Sistiaga P;de Moya-Pinilla M;Martinez-Marcos A
与嗅觉系统平行，大多数哺乳动物具有辅助嗅觉或犁鼻系统。嗅和犁鼻上皮分别投射到主嗅球和副嗅球，主嗅球和副嗅球又分别投射到端脑的邻近区域。新的数据表明，从主要和副嗅球产生的预测部分收敛在头端脑和尾端脑水平不重叠。因此，基底端脑应重新分类为嗅觉区、犁鼻区和混合区。另一方面，它已被证明，几乎所有的嗅觉和犁鼻受体结构发送的主要和副嗅球，分别相互预测。此外，非化学感受受体结构也向嗅球离心投射。这些反馈预测似乎是必不可少的化学感觉信息的调制处理。目前的工作旨在表征离心投影的主要和附属嗅球所产生的嗅觉，犁鼻，混合，和非化学感受受体端脑区。这个问题已经通过在大鼠和小鼠大脑中使用示踪剂注射来解决。示踪剂注射到主要和辅助嗅球以及嗅觉，犁鼻，混合，和非化学感受受体端脑结构。结果证实，嗅觉和犁鼻受体结构项目的主要和副嗅球，分别。有趣的是，嗅觉（例如，梨状皮质），犁鼻（例如，后内侧皮质杏仁核），混合的（例如，前内侧杏仁核），和非化学感受受体（例如，斜角带的核）结构投射到主嗅球和副嗅球，从而提供了在化学感觉处理的不同阶段两个系统的同时调节和相互作用的可能性。
Parallel to the olfactory system, most mammals possess an accessory olfactory or vomeronasal system. The olfactory and vomeronasal epithelia project to the main and accessory olfactory bulbs, which in turn project to adjacent areas of the telencephalon, respectively. New data indicate that projections arising from the main and accessory olfactory bulbs partially converge in the rostral telencephalon and are non-overlapping at caudal telencephalic levels. Therefore, the basal telencephalon should be reclassified in olfactory, vomeronasal, and mixed areas. On the other hand, it has been demonstrated that virtually all olfactory- and vomeronasal-recipient structures send reciprocal projections to the main and accessory olfactory bulbs, respectively. Further, non-chemosensory recipient structures also projects centrifugally to the olfactory bulbs. These feed-back projections appear to be essential modulating processing of chemosensory information. The present work aims at characterizing centrifugal projections to the main and accessory olfactory bulbs arising from olfactory, vomeronasal, mixed, and non-chemosensory recipient telencephalic areas. This issue has been addressed by using tracer injections in the rat and mouse brain. Tracer injections were delivered into the main and accessory olfactory bulbs as well as in olfactory, vomeronasal, mixed, and non-chemosensory recipient telencephalic structures. The results confirm that olfactory- and vomeronasal-recipient structures project to the main and accessory olfactory bulbs, respectively. Interestingly, olfactory (e.g., piriform cortex), vomeronasal (e.g., posteromedial cortical amygdala), mixed (e.g., the anterior medial amygdaloid nucleus), and non-chemosensory-recipient (e.g., the nucleus of the diagonal band) structures project to the main and to the accessory olfactory bulbs thus providing the possibility of simultaneous modulation and interaction of both systems at different stages of chemosensory processing.
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影响因子：
3.3
作者：
Kang, N.;McCarthy, E. A.;Cherry, J. A.;Baum, M. J.
通讯作者：
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影响因子：
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作者：
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Linster, Christiane
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作者：
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