Increased cross-modal functional connectivity in cochlear implant users.
Increased cross-modal functional connectivity in cochlear implant users.
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在人工耳蜗使用者中增加了跨模式功能连接性。
DOI：
10.1038/s41598-017-10792-2
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发表时间：
2017-08-30
影响因子：
4.6
通讯作者：
Debener S
中科院分区：
文献类型：
--
作者：
Chen LC;Puschmann S;Debener S
以往的研究报告增加跨模态的听觉和视觉皮层激活人工耳蜗植入（CI）用户，这表明跨模态重组的视觉和听觉皮层在CI用户的感觉剥夺和恢复的结果。然而，这些过程如何影响CI用户的听觉和视觉系统的功能连接尚不清楚。在这里，我们调查了任务引起的内通道功能连接半球之间的视觉和听觉皮层和跨通道功能连接之间的视觉和听觉皮层使用功能近红外光谱在语言后聋CI用户和年龄匹配的正常听力控制。与对照组相比，CI用户表现出减少的内通道功能连接半球之间的视觉和听觉刺激处理的视觉和左侧听觉皮层之间的跨通道功能连接。重要的是，视觉和听觉刺激的跨模态功能连接之间的差异与CI用户的语音识别结果相关。较高的跨模态连接听觉比视觉刺激与更好的语音识别能力，指向一个新的模式的功能重组，是成功的听力恢复与CI。
Previous studies have reported increased cross-modal auditory and visual cortical activation in cochlear implant (CI) users, suggesting cross-modal reorganization of both visual and auditory cortices in CI users as a consequence of sensory deprivation and restoration. How these processes affect the functional connectivity of the auditory and visual system in CI users is however unknown. We here investigated task-induced intra-modal functional connectivity between hemispheres for both visual and auditory cortices and cross-modal functional connectivity between visual and auditory cortices using functional near infrared spectroscopy in post-lingually deaf CI users and age-matched normal hearing controls. Compared to controls, CI users exhibited decreased intra-modal functional connectivity between hemispheres and increased cross-modal functional connectivity between visual and left auditory cortices for both visual and auditory stimulus processing. Importantly, the difference between cross-modal functional connectivity for visual and for auditory stimuli correlated with speech recognition outcome in CI users. Higher cross-modal connectivity for auditory than for visual stimuli was associated with better speech recognition abilities, pointing to a new pattern of functional reorganization that is related to successful hearing restoration with a CI.
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语前聋青少年听觉、语言和视觉系统内部和之间的灰质连接。
影响因子：
2.8
作者：
Li W;Li J;Wang Z;Li Y;Liu Z;Yan F;Xian J;He H
通讯作者：
He H
影响因子：
3.1
作者：
Chen, Ling-Chia;Sandmann, Pascale;Debener, Stefan
通讯作者：
Debener, Stefan
DOI：
10.1093/cercor/bhl128
发表时间：
2007-09
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Bizley JK;Nodal FR;Bajo VM;Nelken I;King AJ
通讯作者：
King AJ
影响因子：
5.3
作者：
Bavelier, D;Brozinsky, C;Liu, GY
通讯作者：
Liu, GY
影响因子：
2.5
作者：
Herrmann, Bjoern;Henry, Molly J.;Obleser, Jonas
通讯作者：
Obleser, Jonas