Swine influenza virus: Current status and challenge.

Swine influenza virus: Current status and challenge.
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DOI:
10.1016/j.virusres.2020.198118
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发表时间:
2020-10-15
期刊:
影响因子:
5
通讯作者:
Ma W
Ma W
中科院分区:
医学3区
文献类型:
--
作者:
Ma W

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自从1930年首次分离到猪流感病毒以来,它已经成为世界范围内猪的地方病。尽管猪流感疫苗在养猪业得到了大量应用,但猪流感仍无法得到有效控制,已成为养猪业的一种重要经济疾病。在全球猪中流行的不同亚型和基因型的猪流感病毒具有高度的多样性和多样化的分布,这是生产广泛有效的疫苗和控制疾病的主要挑战。重要的是,猪流感病毒能够跨越物种屏障感染人类,甚至在2009年引发流感大流行。本文对猪流感病毒的研究现状和面临的挑战进行了综述和讨论。
Since swine influenza virus was first isolated in 1930, it has become endemic in pigs worldwide. Although large amount of swine influenza vaccines have been used in swine industry, swine influenza still cannot be efficiently controlled and has been an important economic disease for swine industry. The high diversity and varied distribution of different subtypes and genotypes of swine influenza viruses circulating in pigs globally is a major challenge to produce broadly effective vaccines and control disease. Importantly, swine influenza virus is able to cross species barrier to infect humans and even caused influenza pandemic in 2009. Herein, current status and challenge of swine influenza viruses is reviewed and discussed.
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