Mode of delivery, order of birth, parental age gap and autism spectrum disorder among Malaysian children: A case-control study.
Mode of delivery, order of birth, parental age gap and autism spectrum disorder among Malaysian children: A case-control study.
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DOI：
10.1016/j.heliyon.2020.e05068
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发表时间：
2020-10
期刊：
影响因子：
4
通讯作者：
Chidambaram K
中科院分区：
文献类型：
--
作者：
Andoy Galvan JA;Ramalingam PN;Patil SS;Bin Shobri MAS;Chinna K;Sahrir MS;Chidambaram K
在过去的几十年中，自闭症谱系障碍（ASD）的患病率不断上升，导致研究重点放在诊断和识别与ASD相关的因素上。本文旨在寻找使儿童处于ASD风险中的可能因素。在这项研究中，我们调查了ASD和父母年龄之间的关联，父母年龄差距，出生顺序和分娩方式在马来西亚人口。在这项以学校为基础的病例对照研究中，465名ASD儿童464名对照参加。学校透过有关校长向获选儿童的家长派发有关资料。在测试的变量中，剖腹产（OR = 1.63，95%CI 1.20，2.20），家庭中较早的出生顺序（OR = 0.68，95%CI 0.59，0.77）和父母年龄的差距增加（OR = 1.04，95%CI 1.001，1.07）与ASD显著相关。这项研究的结论是，剖腹产，在家庭中出生的顺序和父母年龄差距越来越大的独立风险因素发展中国家的儿童自闭症。流行病学;公共卫生;行为医学;儿科;教育心理学;心理学;认知心理学;自闭症谱系障碍;马来西亚;父母年龄;分娩;出生顺序;父母年龄差距
Rising prevalence of autism spectrum disorders (ASD) in the last decades has led research to focus on the diagnosis and identification of factors associated with ASD. This paper sought for possible factors that put children at risk for ASD. In this study, we investigated the association between ASD and parental ages, parental age gaps, birth order and birth delivery method in Malaysian population. In this school-based case control study, 465 children with ASD 464 controls participated. Questionnaires were distributed to the parents of the selected children through the respective principals. Among the tested variables, Caesarean section (OR = 1.63, 95% CI 1.20, 2.20), earlier order of birth in the family (OR = 0.68, 95% CI 0.59, 0.77) and increasing gap in parental ages (OR = 1.04, 95% CI 1.001, 1.07) were significantly associated with ASD. This study concludes that Caesarean section, earlier order of birth in the family and increasing gap in parental age are independent risk factors for developing autism among Malaysian children. Epidemiology; Public health; Behavioral medicine; Pediatrics; Educational psychology; Psychology; Cognitive psychology; Autism spectrum disorder; Malaysia; Parental age; Birth delivery; Birth order; Parental age gap
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影响因子：
5
作者：
Durkin, Maureen S.;Maenner, Matthew J.;Newschaffer, Craig J.;Lee, Li-Ching;Cunniff, Christopher M.;Daniels, Julie L.;Kirby, Russell S.;Leavitt, Lewis;Miller, Lisa;Zahorodny, Walter;Schieve, Laura A.
通讯作者：
Schieve, Laura A.
DOI：
10.17712/nsj.2019.1.20180303
发表时间：
2019-01
期刊：
Neurosciences (Riyadh, Saudi Arabia)
影响因子：
--
作者：
Al-Zalabani AH;Al-Jabree AH;Zeidan ZA
通讯作者：
Zeidan ZA
影响因子：
2.7
作者：
Husarova VM;Lakatosova S;Pivovarciova A;Babinska K;Bakos J;Durdiakova J;Kubranska A;Ondrejka I;Ostatnikova D
通讯作者：
Ostatnikova D
影响因子：
3.9
作者：
TSAI, LY;STEWART, MA
通讯作者：
STEWART, MA
DOI：
10.1073/pnas.1002601107
发表时间：
2010-06-29
影响因子：
11.1
作者：
Dominguez-Bello, Maria G.;Costello, Elizabeth K.;Knight, Rob
通讯作者：
Knight, Rob