The Rumsfeld paradox: some of the things we know that we don't know about plant virus infection.

The Rumsfeld paradox: some of the things we know that we don't know about plant virus infection.
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拉姆斯菲尔德悖论:关于植物病毒感染,我们知道一些我们不知道的事情。

DOI:
10.1016/j.pbi.2013.06.004
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发表时间:
2013
影响因子:
9.5
通讯作者:
Palukaitis P
Palukaitis P
中科院分区:
生物学2区
文献类型:
--
作者:
Palukaitis P

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重点新的基因发现算法正在揭示隐藏的病毒基因和新的基因表达机制。使用酵母作为植物宿主的代理已经揭示了新的宿主因素。隐性抗性的研究已经揭示了宿主因素的模糊性。光已经被揭示为对病毒抗性的重要新决定因素。植物防御途径可以转向病毒的优势。植物-感染病毒在世界范围内造成显著的作物损失,并且对作物生产的大多数新出现的威胁具有病毒病因学。在理解病毒如何诱导疾病和克服某些形式的抗性,特别是基于RNA沉默的抗性方面,已经取得了重大进展,并将继续取得进展。然而,目前还不清楚其他抗病毒机制是如何工作的,病毒如何成功地利用其宿主,或者病毒如何影响易感植物与其他生物体的相互作用,以及这是否对病毒有利,宿主,或者两者兼而有之。在这篇文章中,我们将探讨这些问题。
HighlightsNew gene-finding algorithms are revealing hidden viral genes and novel gene expression mechanisms.Using yeast as a proxy for plant hosts has revealed novel host factors.Studies of recessive resistance have revealed the ambiguous nature of host factors.Light has been revealed as an important new determinant of resistance to viruses.Plant defensive pathways can be turned to the advantage of the virus.Plant-infecting viruses cause significant crop losses around the world and the majority of emerging threats to crop production have a viral etiology. Significant progress has been made and continues to be made in understanding how viruses induce disease and overcome some forms of resistance–particularly resistance based on RNA silencing. However, it is still not clear how other antiviral mechanisms work, how viruses manage to exploit their hosts so successfully, or how viruses affect the interactions of susceptible plants with other organisms and if this is advantageous to the virus, the host, or both. In this article we explore these questions.
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