The use of collagen cross-linking agents to enhance dentin bond strength.
The use of collagen cross-linking agents to enhance dentin bond strength.
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DOI：
10.1002/jbm.b.31417
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发表时间：
2009-10
影响因子：
3.4
通讯作者：
Bedran-Russo, Ana Karina
中科院分区：
文献类型：
--
作者：
Al-Ammar, Aiman;Drummond, James L.;Bedran-Russo, Ana Karina
I型胶原蛋白是混合层的主要成分，并且其机械性能的改善在粘合过程中可能是有利的。研究三种不同的交联剂（戊二醛[GD]、葡萄籽提取物[GSE]和京尼平[GE]）对树脂-牙本质粘结的拉伸粘结强度（TBS）的影响。收集了64颗健康的人磨牙，并将其咬合面磨平以暴露牙本质。牙本质表面用磷酸蚀刻，然后根据牙本质处理随机分为对照组（未处理）、5%GD、6.5%GSE或0.5%GE。用One Step Plus或Adper Single Bond Plus粘合剂系统和树脂复合材料修复牙齿。24小时后，将牙齿切片以产生1.0mm2的横截面积，并测试拉伸粘结强度。使用ANOVA和Fisher’s PLSD检验对数据进行统计学分析（p< 0.05）。因素之间存在统计学显著的相互作用（处理和粘合剂p<0.001）。治疗影响TBS（p< 0.0001），而粘合系统之间没有观察到差异（p = 0.6961）。GD和GSE促进的对牙本质基质的化学修饰，而不是GE，导致粘结强度增加。选择性胶原交联剂在牙本质粘接修复过程中的应用可能是改善牙本质粘接强度的一种新方法。
Type I collagen is a major component of the hybrid layer, and improvement of its mechanical properties may be advantageous during bonding procedures. To investigate the effect of three different cross-linking agents (Glutaraldehyde [GD], Grape seed extract [GSE], and Genipin [GE]) on the tensile bond strength (TBS) of resin-dentin bonds. Sixty-four sound human molars were collected and their occlusal surfaces were ground flat to expose dentin. Dentin surfaces were etched using a phosphoric acid and then teeth were randomly divided according to the dentin treatment: Control group (no treatment), 5% GD, 6.5% GSE or 0.5% GE. Teeth were restored either with One Step Plus or Adper Single Bond Plus adhesive systems and resin composite. After 24 hours, teeth were sectioned to produce a cross-sectional surface area of 1.0 mm2 and tested for tensile bond strength. Data were statistically analyzed using ANOVA and Fisher's PLSD tests (p< 0.05). There was a statistically significant interaction between factors (treatment and adhesive p<0.001). Treatment affected TBS (p< 0.0001), while no differences were observed between the adhesive systems (p = 0.6961). Chemical modification to the dentin matrix promoted by GD and GSE, but not GE, resulted in increased bond strength. The application of selective collagen cross-linkers during adhesive restorative procedures may be a new approach to improve dentin bond strength properties.
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影响因子：
4.1
作者：
PIERPOINT, WS
通讯作者：
PIERPOINT, WS
影响因子：
4.1
作者：
Tsai, TR;Tseng, TY;Tsai, TH
通讯作者：
Tsai, TH
DOI：
10.1016/0267-6605(92)90098-e
发表时间：
1992-01-01
期刊：
Clinical Materials
影响因子：
--
作者：
YANNAS I V
通讯作者：
YANNAS I V
DOI：
10.1002/jmb.b.31022
发表时间：
2008-08-01
影响因子：
3.4
作者：
Bedran-Russo, Ana Karina B.;Pashley, David H.;Miescke, Klaus J.
通讯作者：
Miescke, Klaus J.
影响因子：
14
作者：
Charulatha, V;Rajaram, A
通讯作者：
Rajaram, A