Dementia in Kerala, South India: prevalence and influence of age, education and gender.
Dementia in Kerala, South India: prevalence and influence of age, education and gender.
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DOI：
10.1002/gps.2338
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发表时间：
2010-03
影响因子：
4
通讯作者：
Sarma, P. S.
中科院分区：
文献类型：
--
作者：
Mathuranath, P. S.;Cherian, P. Joseph;Mathew, Robert;Kumar, Suresh;George, Annamma;Alexander, Aley;Ranjith, Neelima;Sarma, P. S.
关键词：
在人口众多且老龄化的印度，痴呆症患病率的数据很少。我们研究了印度南部喀拉拉邦阿尔茨海默病和痴呆症的患病率，以及年龄、教育程度和性别对其的影响。对2466名年龄≥55岁的社区居民进行两期调查。男性占41%，年龄< 75岁占76.9%，受教育程度≥4年占69.6%。筛查（第一阶段）采用老年人日常生活活动量表（IADL-E）和阿登布鲁克认知测验（ACE）。诊断评估（II期）为532例筛查阳性和247例（10%）筛查阴性。≥55岁93例（3.77%），≥65岁81例（4.86%）。年龄调整后（对照2000年美国人口），≥55岁痴呆（和AD）发生率为4.86%(1.91%)，≥65岁痴呆（和AD）发生率为6.44%（3.56%）。老年痴呆症（和阿尔茨海默氏症）的发病率随着年龄的增长而增加，75-84岁的发病率为5.89(15.33)，≥85岁的发病率为13.23(25.92)，女性为1.62 (2.95)；教育程度≥9年的低0.27（0.16）。年龄和教育程度低会增加痴呆症。年龄和女性增加AD。痴呆症和阿尔茨海默病的患病率高于印度次大陆的任何报告，这表明痴呆症在印度南部喀拉拉邦并不罕见。年龄增长会增加痴呆和阿尔茨海默病。受教育程度低与痴呆和女性阿尔茨海默病有关。
Data on the prevalence of dementia in India with a large and aging population is scant. We studied prevalence of AD and dementia in Kerala, South India, and effects of age, education and gender on it. 2-phase survey on 2466 individuals aged ≥55 years living in community. Men constituted 41%, < 75 years age in 76.9% and education ≥4 years in 69.6%. Screening (Phase I) using the instrumental activity of daily living scale for the elderly (IADL-E) and the Addenbrooke’s cognition examination (ACE). Diagnostic-assessment (Phase II) was in 532 screen-positives and 247 (10%) screen-negatives. 93 (3.77%) ≥55 years and 81 (4.86%) ≥65 years of age had dementia. Age adjusted (against US-population in 2000) dementia (and AD) rates were 4.86% (1.91%) in age ≥55 years and 6.44% (3.56%) in ≥65 years. Odds for dementia (and AD) were high with increasing-age 5.89 (15.33) in 75–84, 13.23 (25.92) ≥85 years, and in women 1.62 (2.95); and low 0.27 (0.16) if education was ≥9 years. Age and low education increased dementia. Age and female gender increased AD. Prevalence of dementia and AD is higher than any reported from the subcontinent suggesting that dementia in Kerala in South India is not uncommon. Increasing age increased dementia and AD. Low-education is associated with dementia and female-gender with AD.
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影响因子：
5.7
作者：
Banerjee, T. K.;Mukherjee, C. S.;Hazra, A.
通讯作者：
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影响因子：
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通讯作者：
Sarma, Sankara P.
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作者：
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通讯作者：
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影响因子：
168.9
作者：
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通讯作者：
Scazufca, M