Modulation of gut microbiota in healthy rats after exposure to nutritional supplements.

Modulation of gut microbiota in healthy rats after exposure to nutritional supplements.
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DOI:
10.1080/19490976.2020.1779002
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发表时间:
2020-11-09
期刊:
影响因子:
12.2
通讯作者:
Kraljević Pavelić S
Kraljević Pavelić S
中科院分区:
医学2区
文献类型:
--
作者:
Čoklo M;Maslov DR;Kraljević Pavelić S

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大鼠是实验动物,经常被用作生物医学研究中的模式生物,并且越来越多地用于研究肠道微生物群。具体而言,后面的研究的目的是阐明肠道生态失调与疾病之间的关系,或者确定可以在肠道微生物群的存在或丰富的情况下引起调节的营养素或药剂。在此,对健康大鼠的肠道微生物群进行的研究以总结和简明的概述形式呈现。重点是旨在揭示暴露于各种类型的营养补充剂后微生物组成和功能变化的研究。我们使用术语“大鼠肠道微生物组微生物群”对PubMed数据库进行了搜索,并检查了旨在评估生理稳态中肠道微生物群组成以及各种营养补充剂对健康大鼠肠道微生物群的影响的研究。
Rats are experimental animals, frequently used as model organisms in the biomedical studies, and increasingly used to study the gut microbiota. Specifically, the aim of latter studies is either the elucidation of relationship between intestinal dysbiosis and diseases or the determination of nutrients or pharmaceutical agents which can cause the modulation in the presence or abundance of gut microbiota. Herein, the research studies conducted on the gut microbiota of healthy rats are presented in a summarized and concise overview. The focus is on studies aimed to reveal the shifts in microbial composition and functional changes after exposure to various types of nutritional supplements. We performed the search of PubMed database using the term “rat gut microbiome microbiota” and examined studies aimed to assess the composition of gut microbiota in physiological homeostasis as well as the effect of various nutritional supplements on the gut microbiota of healthy rats.
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