Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions.
Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions.
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腺病毒的 E3 区:参与宿主免疫监视和病毒与细胞相互作用的基因盒。
DOI:
10.1016/0042-6822(91)90815-s
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发表时间:
1991
期刊:
影响因子:
3.7
通讯作者:
Gooding,LR
中科院分区:
文献类型:
--
作者:
Wold,WS;Gooding,LR
A great deal has been learned about the molecular biology of viruses. However, much less is known at the molecular level about how viruses usurp the infected cell and how they interact with the host’s antiviral defenses. In this review, we will discuss several novel human adenovirus (Ad) proteins, coded mainly within the E3 transcription unit, that may allow adenovirus to evade immunosurveillance and that may prepare the infected cell for efficient virus replication. Several recent reviews are related to this topic (PBBbo et al., 1989; Wold and Gooding, 1989; Gooding and Wold, 1990; Horwitz, 1 QQOa).There are 47 known human adenovirus serotypes (Ad1 to Ad47) that form six distinct groups (A to F). Although adenoviruses in general infect epithelial surfaces of the respiratory and GI tracts, the serotypes and groups can differ markedly in tissue specificity and virulence (Horwitz, 1990b). Ad2 and Ad5 (group C), the most extensively studied, commonly cause respiratory infections in infants and young children. Infections occasionally persist for months or even years; lymphoid cells may be the reservoir for these persistent infections.
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影响因子:
29.7
作者:
and A Townsend;H. Bodmer
通讯作者:
H. Bodmer
DOI:
10.1073/pnas.75.11.5674
发表时间:
1978-01-01
影响因子:
11.1
作者:
KVIST, S;OSTBERG, L;PETERSON, PA
通讯作者:
PETERSON, PA
影响因子:
9.4
作者:
T. Adrian;B. Best;J. Hierholzer;R. Wigand
通讯作者:
R. Wigand
影响因子:
64.5
作者:
Patrick Martin;W. Vass;J. Schiller;D. Lowy;T. Velu
通讯作者:
T. Velu
影响因子:
4.4
作者:
L. Severinsson;I. Martens;P. A. Peterson
通讯作者:
P. A. Peterson